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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 29, 2023
Sep. 30, 2022
Statement of Cash Flows [Abstract]    
Net income $ 122,247 $ 212,455
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation 19,191 14,929
Stock-based compensation 82,039 81,718
Non-cash lease expense 21,475 11,931
Acquired in-process research and development technology 128,500 4,500
Other, net (12,372) 2,890
Changes in operating assets and liabilities:    
Trade receivables, net (33,804) 66,890
Inventory (14,503) (9,836)
Prepaid expenses and other assets 2,430 (35,166)
Accrued collaboration liabilities 1,081 (64,976)
Accounts payable and other liabilities 6,469 3,585
Net cash provided by operating activities 322,753 288,920
Cash flows from investing activities:    
Purchases of investments (823,847) (1,079,411)
Proceeds from maturities and sales of investments 884,989 826,768
Acquired in-process research and development technology (122,500) (8,000)
Purchases of property, equipment and other (27,334) (17,989)
Net cash used in investing activities (88,692) (278,632)
Cash flows from financing activities:    
Payments for repurchases of common stock (341,082) 0
Proceeds from issuance of common stock under equity incentive and stock purchase plans 24,339 18,680
Taxes paid related to net share settlement of equity awards (23,136) (16,091)
Net cash provided by (used in) financing activities (339,879) 2,589
Net increase (decrease) in cash and cash equivalents (105,818) 12,877
Cash and cash equivalents at beginning of period 502,677 663,891
Cash and cash equivalents at end of period 396,859 676,768
Non-cash operating activities:    
Right-of-use assets obtained in exchange for lease obligations $ 13,612 $ 121,958