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Collaboration Agreements And Business Development Activities - Other Collaborations Narrative (Details) - USD ($) $ in Thousands	1 Months Ended	12 Months Ended
	Sep. 29, 2023	Dec. 29, 2023	Dec. 30, 2022	Dec. 31, 2021	Sep. 30, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues		$ 1,830,208	$ 1,611,062	$ 1,434,970
Research and development		1,044,071	891,813	693,716
Collaborative Arrangement with Genentech | Cotellic
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues		16,900	12,500	12,100
Insilico Medicine
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, upfront payment	$ 80,000
Collaborative arrangement, maximum aggregate development milestone payments					$ 100,000
Collaborative arrangement, rights and obligations, maximum aggregate commercial milestone payments					$ 775,000
Research Collaborations, In-Licensing Arrangements and Other Business Development Activities
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, maximum aggregate development milestone payments		774,100
Collaborative arrangement, rights and obligations, maximum aggregate commercial milestone payments		3,893,200
Research and development		173,000	$ 203,900	$ 176,100
Potential regulatory milestone payments		$ 615,500

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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