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Stockholders’ Equity - Estimated Grant-Date Fair Value (Details) - $ / shares
 12 Months Ended
Dec. 29, 2023
Dec. 30, 2022
Dec. 31, 2021
TSR-Based Restricted Stock Units      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]      
Weighted average grant date fair value, awarded (in dollars per share) $ 26.05 $ 33.17  
Fair value of Exelixis common stock on grant date (in dollars per share) $ 19.48 $ 20.70  
Expected volatility 40.26% 46.85%  
Risk-free interest rate 3.75% 1.59%  
Dividend yield 0.00% 0.00%  
Performance stock units      
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]      
Weighted average grant date fair value, awarded (in dollars per share) $ 0   $ 24.54
Fair value of Exelixis common stock on grant date (in dollars per share)     $ 21.31
Expected volatility     49.21%
Risk-free interest rate     0.29%
Dividend yield     0.00%