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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 29, 2023
Dec. 30, 2022
Dec. 31, 2021
Cash flows from operating activities:      
Net income $ 207,765 $ 182,282 $ 231,063
Adjustments to reconcile net income to net cash provided by operating activities:      
Depreciation 25,717 20,875 13,630
Stock-based compensation 106,345 107,574 119,820
Non-cash lease expense 28,976 18,315 5,332
Deferred taxes (133,209) (60,358) 46,529
Acquired in-process research and development technology 128,500 107,250 14,000
Other, net (16,797) (525) 9,443
Changes in operating assets and liabilities:      
Trade receivables, net (22,623) 66,849 (122,324)
Inventory (12,977) (11,683) (13,209)
Prepaid expenses and other assets (29,824) (28,259) (39,875)
Deferred revenue (3,140) (2,483) 11,008
Accrued collaboration liabilities 1,345 (63,065) 70,297
Accounts payable and other liabilities 53,246 25,842 55,090
Net cash provided by operating activities 333,324 362,614 400,804
Cash flows from investing activities:      
Purchases of property, equipment and other (40,469) (27,706) (54,225)
Acquired in-process research and development technology (122,500) (110,750) (10,000)
Purchases of investments (902,468) (1,450,716) (1,357,168)
Proceeds from maturities and sales of investments 1,038,482 1,064,758 1,378,509
Net cash used in investing activities (26,955) (524,414) (42,884)
Cash flows from financing activities:      
Payments for repurchases of common stock (550,378) 0 0
Proceeds from issuance of common stock under equity incentive and stock purchase plans 33,448 23,886 24,307
Taxes paid related to net share settlement of equity awards (29,122) (23,300) (39,108)
Net cash provided by (used in) financing activities (546,052) 586 (14,801)
Net increase (decrease) in cash and cash equivalents (239,683) (161,214) 343,119
Cash and cash equivalents at beginning of period 502,677 663,891 320,772
Cash and cash equivalents at end of period 262,994 502,677 663,891
Supplemental cash flow disclosures:      
Cash paid for taxes 185,658 127,870 12,960
Non-cash operating activities:      
Right-of-use assets obtained in exchange for lease obligations $ 16,623 $ 155,935 $ 4,893