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Segment Reporting - Segment and Consolidated Net Income (Details) - USD ($)
$ in Thousands
 12 Months Ended
Jan. 03, 2025
Dec. 29, 2023
Dec. 30, 2022
Segment Reporting Information [Line Items]      
Revenues $ 2,168,701 $ 1,830,208 $ 1,611,062
Less:      
Cost of goods sold 76,216 72,547 57,909
Interest income (77,156) (86,543) (33,065)
Provision for income taxes 160,373 49,756 52,070
Net income 521,267 207,765 182,282
Reportable Segment      
Segment Reporting Information [Line Items]      
Revenues 2,168,701 1,830,208 1,611,062
Less:      
Cost of goods sold 76,216 72,547 57,909
Drug discovery 94,842 215,085 249,713
Development 665,847 669,240 521,622
Selling, general and administrative 428,962 470,680 397,632
Other segment items 298,350 231,678 182,899
Interest income (77,156) (86,543) (33,065)
Provision for income taxes 160,373 49,756 52,070
Net income $ 521,267 $ 207,765 $ 182,282