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CONSOLIDATED STATEMENTS OF INCOME - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Jan. 03, 2025
Dec. 29, 2023
Dec. 30, 2022
Revenues:      
Total revenues $ 2,168,701 $ 1,830,208 $ 1,611,062
Operating expenses:      
Cost of goods sold 76,216 72,547 57,909
Research and development 910,408 1,044,071 891,813
Selling, general and administrative 492,128 542,705 459,856
Impairment of long-lived assets 51,672 0 0
Restructuring 33,660 0 0
Total operating expenses 1,564,084 1,659,323 1,409,578
Income from operations 604,617 170,885 201,484
Interest income 77,156 86,543 33,065
Other income (expense), net (133) 93 (197)
Income before income taxes 681,640 257,521 234,352
Provision for income taxes 160,373 49,756 52,070
Net income $ 521,267 $ 207,765 $ 182,282
Net income per share:      
Basic (in dollars per share) $ 1.80 $ 0.65 $ 0.57
Diluted (in dollars per share) $ 1.76 $ 0.65 $ 0.56
Weighted-average common shares outstanding:      
Basic (in shares) 290,030 318,151 321,526
Diluted (in shares) 296,132 321,464 324,556
Net product revenues      
Revenues:      
Total revenues $ 1,809,395 $ 1,628,879 $ 1,401,243
License revenues      
Revenues:      
Total revenues 349,244 178,635 162,056
Collaboration services revenues      
Revenues:      
Total revenues $ 10,062 $ 22,694 $ 47,763