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Collaboration Agreements And Business Development Activities - Other Collaborations Narrative (Details) - USD ($) $ in Thousands	12 Months Ended
	Jan. 03, 2025	Dec. 29, 2023	Dec. 30, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues	$ 2,168,701	$ 1,830,208	$ 1,611,062
Research and development	910,408	1,044,071	891,813
Collaborative Arrangement with Genentech | Cotellic
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues	13,600	16,900	12,500
Research Collaborations, In-Licensing Arrangements and Other Business Development Activities
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development	69,200	$ 173,000	$ 203,900
Collaborative arrangement, maximum aggregate development milestone payments	441,500
Potential regulatory milestone payments	278,000
Collaborative arrangement, rights and obligations, maximum aggregate commercial milestone payments	$ 2,400,000

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Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity.

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