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Supplemental Balance Sheet Information - Narrative (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2021 | Jun. 30, 2020 | Jun. 30, 2021 | Jun. 30, 2020 | Dec. 31, 2020 | [1]
Inventory [Line Items] |  |  |  |  |
Inventory | $ 710,975 |  | $ 710,975 |  | $ 698,548
Depreciation expense, net of amounts capitalized into inventory | 11,800 | $ 9,700 | 24,300 | $ 20,000 |
Vosoritide |  |  |  |  |
Inventory [Line Items] |  |  |  |  |
Inventory | $ 9,600 |  | $ 9,600 |  |
[1] | (1)December 31, 2020 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020, filed with the SEC on February 26, 2021.

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