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Financial Instruments - Schedule of Cash, Cash Equivalents and Available-for-Sale Securities by Significant Investment Category (Detail) - USD ($) $ in Thousands	6 Months Ended	12 Months Ended
	Jun. 30, 2021	Dec. 31, 2020
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	$ 1,471,260	$ 1,345,801
Gross Unrealized Gains	2,526	5,069
Gross Unrealized Losses	(152)	(11)
Aggregate Fair Value	1,473,634	1,350,859
Cash and Cash Equivalents	641,533	649,158	[1]
Short-term Marketable Securities	481,864	416,228	[1]
Long-term Marketable Securities	350,237	285,473	[1]
Level 1: | Cash
Schedule of Available-for-sale Securities [Line Items]
Cash	348,830	370,325
Gross Unrealized Gains	0	0
Gross Unrealized Losses	0	0
Aggregate Fair Value	348,830	370,325
Cash and Cash Equivalents	348,830	370,325
Short-term Marketable Securities	0	0
Long-term Marketable Securities	0	0
Level 2:
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	1,122,430	975,476
Gross Unrealized Gains	2,526	5,069
Gross Unrealized Losses	(152)	(11)
Aggregate Fair Value	1,124,804	980,534
Cash and Cash Equivalents	292,703	278,833
Short-term Marketable Securities	481,864	416,228
Long-term Marketable Securities	350,237	285,473
Level 2: | Money market instruments
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	249,556	264,833
Gross Unrealized Gains	0	0
Gross Unrealized Losses	0	0
Aggregate Fair Value	249,556	264,833
Cash and Cash Equivalents	249,556	264,833
Short-term Marketable Securities	0	0
Long-term Marketable Securities	0	0
Level 2: | Corporate debt securities
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	426,514	413,137
Gross Unrealized Gains	1,639	3,261
Gross Unrealized Losses	(110)	(8)
Aggregate Fair Value	428,043	416,390
Cash and Cash Equivalents	0	0
Short-term Marketable Securities	168,393	220,551
Long-term Marketable Securities	259,650	195,839
Level 2: | U.S. government agency securities
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	253,923	265,298
Gross Unrealized Gains	685	1,555
Gross Unrealized Losses	(30)	(1)
Aggregate Fair Value	254,578	266,852
Cash and Cash Equivalents	27,999	14,000
Short-term Marketable Securities	166,491	192,488
Long-term Marketable Securities	60,088	60,364
Level 2: | Commercial paper
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	153,334
Gross Unrealized Gains	3
Gross Unrealized Losses	0
Aggregate Fair Value	153,337
Cash and Cash Equivalents	15,148
Short-term Marketable Securities	138,189
Long-term Marketable Securities	0
Level 2: | Asset-backed securities
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	38,553	31,659
Gross Unrealized Gains	42	85
Gross Unrealized Losses	(12)	(2)
Aggregate Fair Value	38,583	31,742
Cash and Cash Equivalents	0	0
Short-term Marketable Securities	8,282	3,189
Long-term Marketable Securities	30,301	28,553
Level 2: | Foreign and other
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost	550	549
Gross Unrealized Gains	157	168
Gross Unrealized Losses	0	0
Aggregate Fair Value	707	717
Cash and Cash Equivalents	0	0
Short-term Marketable Securities	509	0
Long-term Marketable Securities	$ 198	$ 717
Minimum
Schedule of Available-for-sale Securities [Line Items]
Long term marketable securities maturity period	1 year	1 year
Maximum
Schedule of Available-for-sale Securities [Line Items]
Short term marketable securities maturity period	1 year	1 year
Long term marketable securities maturity period	5 years	5 years
[1] (1)December 31, 2020 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020, filed with the SEC on February 26, 2021.

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