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Revenue, Credit Concentrations and Geographic Information - Disaggregates of Total Revenues from External Customers and Collaborative Partners by Geographic Region (Detail) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Revenue from External Customer [Line Items]        
Total revenues $ 501,693 $ 429,485 $ 987,723 $ 931,554
United States        
Revenue from External Customer [Line Items]        
Total revenues 204,245 232,552 412,431 476,724
Europe        
Revenue from External Customer [Line Items]        
Total revenues 172,678 109,259 334,519 254,295
Latin America        
Revenue from External Customer [Line Items]        
Total revenues 42,248 37,864 101,953 97,788
Rest of world        
Revenue from External Customer [Line Items]        
Total revenues $ 82,522 $ 49,810 $ 138,820 $ 102,747