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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net income $ 30,312 $ 52,198
Adjustments to reconcile net income to net cash used in operating activities:    
Depreciation and amortization 55,214 51,180
Non-cash interest expense 2,082 9,534
Amortization of premium on investments 1,878 38
Stock-based compensation 104,346 91,956
Gain on sale of nonfinancial assets 0 (59,495)
Deferred income taxes 1,204 (5,864)
Unrealized foreign exchange loss (gain) (1,004) 2,201
Non-cash changes in the fair value of contingent consideration 4,488 (584)
Other (376) (650)
Changes in operating assets and liabilities:    
Accounts receivable, net 17,420 (8,028)
Inventory 6,379 (46,298)
Other current assets 34,331 20,441
Other assets 321 (5,599)
Accounts payable and accrued liabilities (60,884) (94,425)
Other long-term liabilities 585 5,938
Net cash provided by operating activities 196,296 12,543
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of property, plant and equipment (48,106) (66,716)
Maturities and sales of investments 348,941 170,111
Purchases of available-for-sale securities (484,572) (321,684)
Proceeds from sale of nonfinancial assets 0 67,159
Purchase of intangible assets (6,400) (10,786)
Investment in convertible note 0 (8,709)
Other (908) (722)
Net cash used in investing activities (191,045) (171,347)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from exercises of awards under equity incentive plans 27,640 46,927
Taxes paid related to net share settlement of equity awards (38,731) (36,645)
Repurchase of common stock 0 (50,000)
Proceeds from convertible senior subordinated note offering, net 0 585,782
Principal repayments of financing leases (1,941) (2,047)
Other (381) 0
Net cash provided by (used in) financing activities (13,413) 544,017
Effect of exchange rate changes on cash 537 (3,759)
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS (7,625) 381,454
Cash and cash equivalents:    
Beginning of period 649,158 437,446
End of period 641,533 818,900
SUPPLEMENTAL CASH FLOW DISCLOSURES:    
Cash paid for income taxes 10,159 2,960
Cash paid for interest 5,195 4,154
SUPPLEMENTAL CASH FLOW DISCLOSURES FOR NON-CASH INVESTING AND FINANCING ACTIVITIES:    
Decrease in accounts payable and accrued liabilities related to fixed assets (9,393) (23,259)
Increase (decrease) in accounts payable and accrued liabilities related to intangible assets $ 1,397 $ (2,523)