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Financial Instruments - Schedule of Cash, Cash Equivalents and Available-for-Sale Securities by Significant Investment Category (Detail) - USD ($) $ in Thousands | 9 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2021 | Dec. 31, 2020
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | $ 1,544,506 | $ 1,345,801 |
Gross Unrealized Gains | 1,823 | 5,069 |
Gross Unrealized Losses | (235) | (11) |
Aggregate Fair Value | 1,546,094 | 1,350,859 |
Cash and Cash Equivalents | 617,143 | 649,158 | [1]
Short-term Marketable Securities | 462,333 | 416,228 | [1]
Long-term Marketable Securities | 466,618 | 285,473 | [1]
Level 1: | Cash |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Cash | 294,209 | 370,325 |
Gross Unrealized Gains | 0 | 0 |
Gross Unrealized Losses | 0 | 0 |
Aggregate Fair Value | 294,209 | 370,325 |
Cash and Cash Equivalents | 294,209 | 370,325 |
Short-term Marketable Securities | 0 | 0 |
Long-term Marketable Securities | 0 | 0 |
Level 2: |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 1,250,297 | 975,476 |
Gross Unrealized Gains | 1,823 | 5,069 |
Gross Unrealized Losses | (235) | (11) |
Aggregate Fair Value | 1,251,885 | 980,534 |
Cash and Cash Equivalents | 322,934 | 278,833 |
Short-term Marketable Securities | 462,333 | 416,228 |
Long-term Marketable Securities | 466,618 | 285,473 |
Level 2: | Money market instruments |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 291,735 | 264,833 |
Gross Unrealized Gains | 0 | 0 |
Gross Unrealized Losses | 0 | 0 |
Aggregate Fair Value | 291,735 | 264,833 |
Cash and Cash Equivalents | 291,735 | 264,833 |
Short-term Marketable Securities | 0 | 0 |
Long-term Marketable Securities | 0 | 0 |
Level 2: | Corporate debt securities |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 560,004 | 413,137 |
Gross Unrealized Gains | 1,230 | 3,261 |
Gross Unrealized Losses | (198) | (8) |
Aggregate Fair Value | 561,036 | 416,390 |
Cash and Cash Equivalents | 703 | 0 |
Short-term Marketable Securities | 177,468 | 220,551 |
Long-term Marketable Securities | 382,865 | 195,839 |
Level 2: | U.S. government agency securities |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 210,444 | 265,298 |
Gross Unrealized Gains | 416 | 1,555 |
Gross Unrealized Losses | (7) | (1) |
Aggregate Fair Value | 210,853 | 266,852 |
Cash and Cash Equivalents | 12,999 | 14,000 |
Short-term Marketable Securities | 161,207 | 192,488 |
Long-term Marketable Securities | 36,647 | 60,364 |
Level 2: | Commercial paper |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 129,818 |  |
Gross Unrealized Gains | 1 |  |
Gross Unrealized Losses | (1) |  |
Aggregate Fair Value | 129,818 |  |
Cash and Cash Equivalents | 17,497 |  |
Short-term Marketable Securities | 112,321 |  |
Long-term Marketable Securities | 0 |  |
Level 2: | Asset-backed securities |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 55,182 | 31,659 |
Gross Unrealized Gains | 26 | 85 |
Gross Unrealized Losses | (23) | (2) |
Aggregate Fair Value | 55,185 | 31,742 |
Cash and Cash Equivalents | 0 | 0 |
Short-term Marketable Securities | 8,272 | 3,189 |
Long-term Marketable Securities | 46,913 | 28,553 |
Level 2: | Foreign and other |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Amortized Cost | 3,114 | 549 |
Gross Unrealized Gains | 150 | 168 |
Gross Unrealized Losses | (6) | 0 |
Aggregate Fair Value | 3,258 | 717 |
Cash and Cash Equivalents | 0 | 0 |
Short-term Marketable Securities | 3,065 | 0 |
Long-term Marketable Securities | $ 193 | $ 717 |
Minimum |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Long term marketable securities maturity period | 1 year | 1 year |
Maximum |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |
Short term marketable securities maturity period | 1 year | 1 year |
Long term marketable securities maturity period | 5 years | 5 years |
[1] | (1)December 31, 2020 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020, filed with the SEC on February 26, 2021.

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