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Revenue, Credit Concentrations and Geographic Information - Disaggregates of Total Revenues from External Customers and Collaborative Partners by Geographic Region (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Revenue from External Customer [Line Items]        
Total revenues $ 408,742 $ 476,784 $ 1,396,465 $ 1,408,338
United States        
Revenue from External Customer [Line Items]        
Total revenues 196,239 252,948 608,670 729,672
Europe        
Revenue from External Customer [Line Items]        
Total revenues 115,497 121,158 450,016 375,453
Latin America        
Revenue from External Customer [Line Items]        
Total revenues 38,958 44,064 140,911 141,852
Rest of world        
Revenue from External Customer [Line Items]        
Total revenues $ 58,048 $ 58,614 $ 196,868 $ 161,361