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INCOME TAXES - Summary of Expiration of not Utilized Net Operating Loss and Tax Credit Carryforwards (Detail) $ in Thousands | Dec. 31, 2021 USD ($)
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Federal |
Income Tax Contingency [Line Items] |
Net operating loss carryforwards | $ 4,147
Federal R&D and orphan drug credit carryforwards | 592,710
State |
Income Tax Contingency [Line Items] |
Net operating loss carryforwards | 230,500
Federal R&D and orphan drug credit carryforwards | 137,300
Dutch | Foreign |
Income Tax Contingency [Line Items] |
Net operating loss carryforwards | $ 48,903

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