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Supplemental Financial Statements Information - Narrative (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2021 | [1]
Inventory [Line Items] |  |  |  |  |
Inventory | $ 802,315 |  | $ 802,315 |  | $ 776,669
Depreciation expense, net of amounts capitalized into inventory | 9,500 | $ 11,800 | 21,200 | $ 24,300 |
Gain on sale of nonfinancial assets, net | 0 | $ 0 | 108,000 | $ 0 |
Valoctocogene Roxaparvovec |  |  |  |  |
Inventory [Line Items] |  |  |  |  |
Inventory | $ 31,800 |  | $ 31,800 |  |
[1] | (1)December 31, 2021 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2021, filed with the SEC on February 25, 2022.

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