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Revenue, Credit Concentrations and Geographic Information - Total Net Product Revenue Concentrations Attributed to Largest Customers (Detail) - Customer Concentration Risk - Net Product Revenue	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Customer A, B, & C
Concentration Risk [Line Items]
Concentration risk, percentage	33.00%	41.00%	33.00%	39.00%
Customer A
Concentration Risk [Line Items]
Concentration risk, percentage	16.00%	16.00%	16.00%	16.00%
Customer B
Concentration Risk [Line Items]
Concentration risk, percentage	12.00%	13.00%	12.00%	13.00%
Customer C
Concentration Risk [Line Items]
Concentration risk, percentage	5.00%	12.00%	5.00%	10.00%

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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