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BUSINESS OVERVIEW AND SIGNIFICANT ACCOUNTING POLICIES (Details) $ in Thousands | 9 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | ---
Sep. 30, 2022 USD ($) commercial_product | Jun. 30, 2022 USD ($) | Dec. 31, 2021 USD ($) | Sep. 30, 2021 USD ($) | Jun. 30, 2021 USD ($) | Dec. 31, 2020 USD ($)
Change in Accounting Estimate [Line Items] |  |  |  |  |  |  |
Number of commercial products in portfolio | commercial_product | 8 |  |  |  |  |  |
Accumulated deficit | $ 788,949 |  | $ 930,759 | [1] |  |  |
Decrease in stockholders’ equity | (4,568,514) | $ (4,499,737) | (4,265,670) | [1] | $ (4,261,078) | $ (4,236,500) | $ (4,100,931)
Deferred tax assets | 1,455,205 |  | 1,450,161 | [1] |  |  |
Other assets | 151,788 |  | 152,121 | [1] |  |  |
Other long-term liabilities | $ (92,473) |  | (98,361) | [1] |  |  |
Revision of Prior Period, Error Correction, Adjustment |  |  |  |  |  |  |
Change in Accounting Estimate [Line Items] |  |  |  |  |  |  |
Accumulated deficit |  |  |  |  |  |  | 5,100
Decrease in stockholders’ equity |  | $ 5,071 | 5,071 |  |  | $ 5,071 | $ 5,071
Accounts payable and accrued liabilities |  |  | 6,700 |  |  |  |
Deferred tax assets |  |  | 1,100 |  |  |  |
Other assets |  |  | 400 |  |  |  |
Other long-term liabilities |  |  | $ 100 |  |  |  |
[1] | (1)Certain December 31, 2021 balances have been corrected for an immaterial error identified in the third quarter of 2022. See Note 1 to these Condensed Consolidated Financial Statements for details.

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