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REVENUE, CREDIT CONCENTRATIONS AND GEOGRAPHIC INFORMATION - Disaggregates of Net Product Revenues by Product (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Revenue from External Customer [Line Items] |  |  |  |
Revenue | $ 505,344 | $ 408,742 | $ 1,558,501 | $ 1,396,465
Product |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 493,348 | 393,840 | 1,516,533 | 1,348,279
VIMIZIM | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 155,470 | 136,744 | 511,735 | 466,697
NAGLAZYME | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 99,506 | 71,172 | 343,320 | 297,321
PALYNZIQ | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 66,206 | 60,729 | 182,734 | 173,702
KUVAN | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 57,038 | 67,687 | 173,977 | 217,257
VOXZOGO | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 48,289 | 144 | 102,321 | 144
BRINEURA | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 37,793 | 32,984 | 111,691 | 90,641
Total net product revenues marketed by the Company | Marketed by Company |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 464,302 | 369,460 | 1,425,778 | 1,245,762
ALDURAZYME net product revenues marketed by Sanofi | Marketed by Sanofi |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 29,046 | 24,380 | 90,755 | 102,517
Royalty and other revenues |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | $ 11,996 | $ 14,902 | $ 41,968 | $ 48,186

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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8906-108599 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 40 -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e9031-108599 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e9038-108599 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (b) -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8933-108599 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8933-108599 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 4 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130543-203045 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (b) -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8736-108599 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e8736-108599 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 42 -URI https://asc.fasb.org/extlink&oid=126901519&loc=d3e9054-108599 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 5 -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130545-203045 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 924 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 11.L) -URI https://asc.fasb.org/extlink&oid=6472922&loc=d3e499488-122856 + Details
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