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INCOME TAXES - Summary of Expiration of not Utilized Net Operating Loss and Tax Credit Carryforwards (Details) $ in Thousands | Dec. 31, 2022 USD ($)
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Federal |
Income Tax Contingency [Line Items] |
Net operating loss carryforwards | $ 3,628
Federal R&D and orphan drug credit carryforwards | 585,322
State |
Income Tax Contingency [Line Items] |
Net operating loss carryforwards | 186,594
Federal R&D and orphan drug credit carryforwards | 152,700
Dutch | Foreign |
Income Tax Contingency [Line Items] |
Net operating loss carryforwards, not subject to expiration | $ 38,912

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