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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
 [1]
REVENUES:      
Total revenues $ 2,096,039 $ 1,846,275 $ 1,860,455
OPERATING EXPENSES:      
Cost of sales 483,669 470,515 524,272
Research and development 649,606 628,793 628,116
Selling, general and administrative 854,009 759,375 737,669
Intangible asset amortization and contingent consideration 67,193 69,933 66,658
Gain on sale of nonfinancial assets, net (108,000) 0 (52,820)
Total operating expenses 1,946,477 1,928,616 1,903,895
INCOME (LOSS) FROM OPERATIONS 149,562 (82,341) (43,440)
Interest income 18,034 10,482 16,610
Interest expense (15,970) (15,337) (29,309)
Other income (expense), net (2,050) 11,846 7,142
INCOME (LOSS) BEFORE INCOME TAXES 149,576 (75,350) (48,997)
Provision for (benefit from) income taxes 8,015 (11,270) (903,026)
NET INCOME (LOSS) $ 141,561 $ (64,080) $ 854,029 [2],[3]
EARNINGS (LOSS) PER SHARE, BASIC (in dollars per share) $ 0.76 $ (0.35) $ 4.72
EARNINGS (LOSS) PER SHARE, DILUTED (in dollars per share) $ 0.75 $ (0.35) $ 4.50
Weighted-average common shares outstanding, basic (in shares) 185,266 182,852 180,804
Weighted average common shares outstanding, diluted (in shares) 188,963 182,852 191,678
Net product revenues      
REVENUES:      
Total revenues $ 2,042,025 $ 1,783,498 $ 1,805,861
Royalty and other revenues      
REVENUES:      
Total revenues $ 54,014 $ 62,777 $ 54,594
[1] Certain December 31, 2020 amounts have been corrected for an immaterial error identified in the third quarter of 2022. See Note 1 to these Consolidated Financial Statements for details.
[2] Certain December 31, 2020 balances have been corrected for an immaterial error identified in the third quarter of 2022. See Note 1 to these Consolidated Financial Statements for details.
[3] December 31, 2020 Net Income has been corrected for an immaterial error identified in the third quarter of 2022. See Note 1 to these Consolidated Financial Statements for details.