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INCOME TAXES - Schedule of Effective Income Tax Rate Reconciliation (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Income Tax Contingency [Line Items]
Federal statutory income tax rate	$ 31,412	$ (15,824)	$ (10,289)
State and local taxes	(1,017)	509	(3,467)
Orphan Drug & General Business Credit	(35,674)	(29,363)	(44,114)
Stock compensation expense	6,433	7,859	(1,101)
Foreign Source Income Subject to US Tax	(5,644)	16,878	6,266
Foreign tax rate differential	(4,051)	(16,971)	(16,238)
Section 162(m) limitation	6,577	6,304	9,571
Tax Reserves	18,043	15,530	2,166
Intra-entity transfer of assets	(18,752)	(3,920)	(852,338)
CARES act carryback claim	0	0	(2,201)
Valuation allowance/deferred benefit	7,851	6,821	6,876
Other	2,837	907	1,843
Effective income tax rate	8,015	(11,270)	$ (903,026)	[1]
Valuation allowance	$ 116,299	109,176
Dutch
Income Tax Contingency [Line Items]
Valuation allowance		$ 9,300
[1] Certain December 31, 2020 amounts have been corrected for an immaterial error identified in the third quarter of 2022. See Note 1 to these Consolidated Financial Statements for details.

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