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REVENUE, CREDIT CONCENTRATIONS AND GEOGRAPHIC INFORMATION - Disaggregates of Net Product Revenues by Product (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022
Revenue from External Customer [Line Items] |  |  |  |
Revenue | $ 595,275 | $ 533,798 | $ 1,191,690 | $ 1,053,157
Product |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 584,698 | 517,660 | 1,171,124 | 1,023,185
Total enzyme product revenues |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 420,739 | 425,684 | 868,851 | 852,214
VIMIZIM |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 177,392 | 173,206 | 366,584 | 356,265
NAGLAZYME |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 90,103 | 115,783 | 213,124 | 243,814
PALYNZIQ |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 74,868 | 61,643 | 137,220 | 116,528
ALDURAZYME |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 40,318 | 37,327 | 74,721 | 61,709
BRINEURA |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 38,058 | 37,725 | 77,202 | 73,898
VOXZOGO |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 113,337 | 34,374 | 201,173 | 54,032
KUVAN |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | 50,622 | 57,602 | 101,100 | 116,939
Royalty and other revenues |  |  |  |
Revenue from External Customer [Line Items] |  |  |  |
Revenue | $ 10,577 | $ 16,138 | $ 20,566 | $ 29,972

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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 924 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 11.L) -Publisher FASB -URI https://asc.fasb.org//1943274/2147479941/924-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 606 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 5 -Publisher FASB -URI https://asc.fasb.org//1943274/2147479806/606-10-50-5 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 30 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 42 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-42 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 40 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-40 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 41 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-41 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Topic 606 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 4 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147479806/606-10-50-4 + Details
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