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PROPERTY, PLANT AND EQUIPMENT | 12 Months Ended
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Dec. 31, 2023
Property, Plant and Equipment [Abstract] |
PROPERTY, PLANT AND EQUIPMENT | PROPERTY, PLANT AND EQUIPMENT Property, Plant and Equipment, Net, consisted of the following:
| December 31
| 2023 |  | 2022
Building and improvements | $ | 860,807 |  |  | $ | 819,100 |
Manufacturing and laboratory equipment | 538,677 |  |  | 475,663 |
Computer hardware and software | 211,482 |  |  | 214,829 |
Land | 90,781 |  |  | 90,786 |
Leasehold improvements | 58,230 |  |  | 59,532 |
Furniture and equipment | 46,453 |  |  | 45,762 |
Land improvements | 26,779 |  |  | 26,455 |
Construction-in-progress (1) | 100,013 |  |  | 143,384 |
| 1,933,222 |  |  | 1,875,511 |
Accumulated depreciation | (867,089) |  |  | (802,145) |
Total property, plant and equipment, net | $ | 1,066,133 |  |  | $ | 1,073,366 |
(1)In the fourth quarter of 2023, the Company decided to cease development of the first generation VOXZOGO pen device and impaire d $14.0 million of capitalized tooling and fixed assets that had not been placed in service. Depreciation expense, net of amounts capitalized into inventory, was $40.3 million, $38.6 million and $46.1 million for the years ended December 31, 2023, 2022 and 2021, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org//360/tableOfContent Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 6 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480321/958-360-50-6 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480321/958-360-50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 7 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480321/958-360-50-7 + Details
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