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REVENUE, CREDIT CONCENTRATIONS AND GEOGRAPHIC INFORMATION - Schedule of Total Revenues and Disaggregates Net Product Revenues by Product (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Revenue from External Customer [Line Items] |  |  |
Revenue | $ 2,419,226 | $ 2,096,039 | $ 1,846,275
Product |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 2,372,538 | 2,042,025 | 1,783,498
Total enzyme product revenues |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 1,718,401 | 1,645,320 | 1,491,867
VIMIZIM |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 701,053 | 663,739 | 623,145
NAGLAZYME |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 420,292 | 443,794 | 380,449
PALYNZIQ |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 303,919 | 255,032 | 237,474
BRINEURA |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 161,889 | 154,333 | 128,034
ALDURAZYME |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 131,248 | 128,422 | 122,765
ALDURAZYME | Marketed by Sanofi |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 131,248 | 128,422 | 122,765
VOXZOGO |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 469,881 | 169,128 | 5,855
KUVAN |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 180,767 | 227,577 | 285,776
ROCTAVIAN |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | 3,489 | 0 | 0
Royalty and other revenues |  |  |
Revenue from External Customer [Line Items] |  |  |
Revenue | $ 46,688 | $ 54,014 | $ 62,777

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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 924 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 11.L) -Publisher FASB -URI https://asc.fasb.org//1943274/2147479941/924-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 606 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 5 -Publisher FASB -URI https://asc.fasb.org//1943274/2147479806/606-10-50-5 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 30 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-30 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 42 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-42 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 40 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-40 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-22 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-32 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 41 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482810/280-10-50-41 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Topic 606 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 4 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147479806/606-10-50-4 + Details
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