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PROPERTY, PLANT AND EQUIPMENT | 12 Months Ended
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Dec. 31, 2024
Property, Plant and Equipment [Abstract] |
PROPERTY, PLANT AND EQUIPMENT | PROPERTY, PLANT AND EQUIPMENT Property, Plant and Equipment, Net, consisted of the following:
| December 31
| 2024 |  | 2023
Building and improvements | $ | 892,484 |  |  | $ | 860,807 |
Manufacturing and laboratory equipment | 542,856 |  |  | 538,677 |
Computer hardware and software | 204,768 |  |  | 211,482 |
Land | 90,781 |  |  | 90,781 |
Leasehold improvements | 44,368 |  |  | 58,230 |
Furniture and equipment | 41,871 |  |  | 46,453 |
Land improvements | 27,433 |  |  | 26,779 |
Construction-in-progress | 90,271 |  |  | 100,013 |
| 1,934,832 |  |  | 1,933,222 |
Accumulated depreciation | (891,791) |  |  | (867,089) |
Total property, plant and equipment, net | $ | 1,043,041 |  |  | $ | 1,066,133 |
Depreciation expense, net of amounts capitalized into inventory, was $46.6 million, $40.3 million and $38.6 million for the years ended December 31, 2024, 2023 and 2022, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org/360/tableOfContent Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 6 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-6 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 7 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org/1943274/2147477798/958-360-50-7 + Details
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