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SEGMENT INFORMATION - Schedule of Total Revenues and Disaggregates Net Product Revenues by Product (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Revenue from External Customer [Line Items] |  |  |
Total revenues | $ 2,853,915 | $ 2,419,226 | $ 2,096,039
Product |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 2,809,445 | 2,372,538 | 2,042,025
VIMIZIM |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 739,784 | 701,053 | 663,739
VOXZOGO |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 735,092 | 469,881 | 169,128
NAGLAZYME |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 479,584 | 420,292 | 443,794
PALYNZIQ |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 355,047 | 303,919 | 255,032
ALDURAZYME |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 183,887 | 131,248 | 128,422
BRINEURA |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 169,083 | 161,889 | 154,333
KUVAN |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 120,902 | 180,767 | 227,577
ROCTAVIAN |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | 26,066 | 3,489 | 0
Royalty and other revenues |  |  |
Revenue from External Customer [Line Items] |  |  |
Total revenues | $ 44,470 | $ 46,688 | $ 54,014

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