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SEGMENT INFORMATION - Schedule of Total Revenues and Disaggregates Net Product Revenues by Product (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenue from External Customer [Line Items]        
Total revenues $ 776,133 $ 745,740 $ 2,346,688 $ 2,106,602
Net product revenues        
Revenue from External Customer [Line Items]        
Total revenues 760,812 733,867 2,308,438 2,073,811
VOXZOGO        
Revenue from External Customer [Line Items]        
Total revenues 218,387 189,785 653,532 526,597
VIMIZIM        
Revenue from External Customer [Line Items]        
Total revenues 182,755 178,158 586,525 548,694
NAGLAZYME        
Revenue from External Customer [Line Items]        
Total revenues 122,025 131,906 365,182 369,584
PALYNZIQ        
Revenue from External Customer [Line Items]        
Total revenues 108,778 90,634 307,985 254,634
ALDURAZYME        
Revenue from External Customer [Line Items]        
Total revenues 53,709 71,029 159,123 144,849
BRINEURA        
Revenue from External Customer [Line Items]        
Total revenues 47,953 37,005 137,007 121,361
KUVAN        
Revenue from External Customer [Line Items]        
Total revenues 24,025 28,115 76,195 92,576
ROCTAVIAN        
Revenue from External Customer [Line Items]        
Total revenues 3,180 7,235 22,889 15,516
Royalty and other revenues        
Revenue from External Customer [Line Items]        
Total revenues $ 15,321 $ 11,873 $ 38,250 $ 32,791