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  <xsd:import namespace="http://fasb.org/us-gaap/2024" schemaLocation="https://xbrl.fasb.org/us-gaap/2024/elts/us-gaap-2024.xsd" />
  <xsd:import namespace="http://fasb.org/srt/2024" schemaLocation="https://xbrl.fasb.org/srt/2024/elts/srt-2024.xsd" />
  <xsd:import namespace="http://xbrl.sec.gov/ecd-sub/2024" schemaLocation="https://xbrl.sec.gov/ecd/2024/ecd-sub-2024.xsd" />
  <xsd:element abstract="false" id="ssb_OtherRealEstateOwnedExpenseAndLoanRelated" name="OtherRealEstateOwnedExpenseAndLoanRelated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_EarningsAbstract" name="EarningsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_AccretionOnLoansCoveredUnderFdicLossShareAgreements" name="AccretionOnLoansCoveredUnderFdicLossShareAgreements" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="credit" />
  <xsd:element abstract="true" id="ssb_CashPaidAbstract" name="CashPaidAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_InvestmentSecuritiesDisclosureAbstract" name="InvestmentSecuritiesDisclosureAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_DepositsDisclosureAbstract" name="DepositsDisclosureAbstract" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_StockRepurchaseProgramAndOtherRepurchaseArrangementsDisclosureAbstract" name="StockRepurchaseProgramAndOtherRepurchaseArrangementsDisclosureAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_CertificatesOfDeposit250000OrMore" name="CertificatesOfDeposit250000OrMore" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="ssb_OtherRealEstateMember" name="OtherRealEstateMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_ImpairedLoansMember" name="ImpairedLoansMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_NonAcquiredLoansMember" name="NonAcquiredLoansMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_AcquiredLoansMember" name="AcquiredLoansMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_ScheduleOfOtherInvestmentSecuritiesReconciliationTableTextBlock" name="ScheduleOfOtherInvestmentSecuritiesReconciliationTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_EmploymentStatusAxis" name="EmploymentStatusAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_EmploymentStatusDomain" name="EmploymentStatusDomain" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_DefinedContributionPlanEmployeeContributionAsPercentageOfAnnualBaseCompensation" name="DefinedContributionPlanEmployeeContributionAsPercentageOfAnnualBaseCompensation" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualTermAbstract" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualTermAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIntrinsicValueAbstract" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIntrinsicValueAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_ScheduleOfFairValueByBalanceSheetGroupingAndOffBalanceSheetRisksTable" name="ScheduleOfFairValueByBalanceSheetGroupingAndOffBalanceSheetRisksTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_FairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTableTextBlock" name="FairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_FairValueBalanceSheetGroupingFinancialStatementCaptionsAndOffBalanceSheetRisksDisclosureInformationLineItems" name="FairValueBalanceSheetGroupingFinancialStatementCaptionsAndOffBalanceSheetRisksDisclosureInformationLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_ScheduleOfDefinedContributionBenefitPlansDisclosuresLineItems" name="ScheduleOfDefinedContributionBenefitPlansDisclosuresLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_DefinedContributionPlanAgeOfEmployeesCovered" name="DefinedContributionPlanAgeOfEmployeesCovered" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_ScheduleOfFinancingReceivablesChangesInNonAccrualStatusTableTextBlock" name="ScheduleOfFinancingReceivablesChangesInNonAccrualStatusTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_CommercialNonOwnerOccupiedRealEstateLoansMember" name="CommercialNonOwnerOccupiedRealEstateLoansMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_CommercialAndIndustrialLoansMember" name="CommercialAndIndustrialLoansMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_OtherIncomeProducingPropertyLoansMember" name="OtherIncomeProducingPropertyLoansMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLoansReceivable" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLoansReceivable" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDepositLiabilities" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDepositLiabilities" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element abstract="true" id="ssb_SubstandardAndDoubtfulMember" name="SubstandardAndDoubtfulMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_DefinedContributionPlanEmployerContributionPercent" name="DefinedContributionPlanEmployerContributionPercent" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_CommitmentsToExtendCreditAndStandbyLettersOfCredit" name="CommitmentsToExtendCreditAndStandbyLettersOfCredit" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="ssb_AllowanceForCreditLossesLoansThatSubsequentlyDefaulted" name="AllowanceForCreditLossesLoansThatSubsequentlyDefaulted" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssuedExchangeRatio" name="BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssuedExchangeRatio" nillable="true" type="xbrli:pureItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsAdditionalDisclosuresAbstract" name="OtherThanTemporaryImpairmentCreditLossesRecognizedInEarningsAdditionalDisclosuresAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_OtherStockRepurchaseArrangementsWithDirectorsOrOfficersMember" name="OtherStockRepurchaseArrangementsWithDirectorsOrOfficersMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardPerformancePeriod" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardPerformancePeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_LengthOfTimeWithSustainedRepaymentPerformanceToReturnToAccruingStatus" name="LengthOfTimeWithSustainedRepaymentPerformanceToReturnToAccruingStatus" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_ResidentialMortgageServicingRightsFairValueDisclosure" name="ResidentialMortgageServicingRightsFairValueDisclosure" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="false" id="ssb_ScheduleOfFiniteLivedIntangibleAssetsFutureAmortizationExpenseForEachOfNextQuartersTableTextBlock" name="ScheduleOfFiniteLivedIntangibleAssetsFutureAmortizationExpenseForEachOfNextQuartersTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_MortgageLoanPipelineMember" name="MortgageLoanPipelineMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_ExpectedClosuresMember" name="ExpectedClosuresMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_ChangesInFairValueOfMortgageServicingRightsMSRAndOffsettingHedgeAbstract" name="ChangesInFairValueOfMortgageServicingRightsMSRAndOffsettingHedgeAbstract" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_DerivativeFairValueAndObligationAndFairValueOfAssociatedDerivativeInstrumentsAbstract" name="DerivativeFairValueAndObligationAndFairValueOfAssociatedDerivativeInstrumentsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_ScheduleOfChangesInFairValueOfMortgageServicingRightsAndOffsettingHedgeTableTextBlock" name="ScheduleOfChangesInFairValueOfMortgageServicingRightsAndOffsettingHedgeTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_ScheduleOfDerivativeFairValueAndObligationAndFairValueOfAssociatedDerivativeInstrumentsTableTextBlock" name="ScheduleOfDerivativeFairValueAndObligationAndFairValueOfAssociatedDerivativeInstrumentsTableTextBlock" nillable="true" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_LoansHeldForSaleLoanServicingAndMortgageOriginationDisclosureAbstract" name="LoansHeldForSaleLoanServicingAndMortgageOriginationDisclosureAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_ScheduleOfCompositionOfResidentialMortgagesServicedForOthersAndCharacteristicsAndSensitivityAnalysisOfMortgageServicingRightsTableTextBlock" name="ScheduleOfCompositionOfResidentialMortgagesServicedForOthersAndCharacteristicsAndSensitivityAnalysisOfMortgageServicingRightsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_ResidentialMortgagesServicedForOthers" name="ResidentialMortgagesServicedForOthers" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_ResidentialMortgagesServicedForOthersPercentage" name="ResidentialMortgagesServicedForOthersPercentage" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="ssb_SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOfChangeInAssumptionAbstract" name="SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOfChangeInAssumptionAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf25BasisPointIncreaseInInterestRates" name="SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf25BasisPointIncreaseInInterestRates" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="false" id="ssb_SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf50BasisPointIncreaseInInterestRates" name="SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf50BasisPointIncreaseInInterestRates" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="ssb_SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf25BasisPointDecreaseInInterestRates" name="SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf25BasisPointDecreaseInInterestRates" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element abstract="false" id="ssb_SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf50BasisPointDecreaseInInterestRates" name="SensitivityAnalysisOfFairValueOfInterestsContinuedToBeHeldByTransferorServicingAssetsOrLiabilitiesImpactOf50BasisPointDecreaseInInterestRates" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="ssb_ResidentialMortgageLoansAwaitingSaleInSecondaryMarketMember" name="ResidentialMortgageLoansAwaitingSaleInSecondaryMarketMember" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_MortgageLoanSecuritizationsAndSalesAbstract" name="MortgageLoanSecuritizationsAndSalesAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_MortgageLoanSold" name="MortgageLoanSold" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_MortgageLoanSecuritizationsAndSales" name="MortgageLoanSecuritizationsAndSales" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="false" id="ssb_LoansHeldForSaleSettlementPeriod" name="LoansHeldForSaleSettlementPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_CashFlowInformationAbstract" name="CashFlowInformationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_LossCoveredUnderLossShareAgreementsAxis" name="LossCoveredUnderLossShareAgreementsAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="ssb_LossCoveredUnderLossShareAgreementsDomain" name="LossCoveredUnderLossShareAgreementsDomain" nillable="true" substitutionGroup="xbrli:item" type="dtr-types:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="ssb_PercentageOfMortgageLoanSecuritizationsAndSales" name="PercentageOfMortgageLoanSecuritizationsAndSales" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ssb_RealEstateAcquiredInFullOrInPartialSettlementOfLoans" name="RealEstateAcquiredInFullOrInPartialSettlementOfLoans" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssets" name="CommonEquityTierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssets" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConversionBuffer" name="CommonEquityTierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConversionBuffer" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapitalAbstract" name="CommonEquityTierOneRiskBasedCapitalAbstract" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapital" name="CommonEquityTierOneRiskBasedCapital" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapitalRequiredToBeWellCapitalized" name="CommonEquityTierOneRiskBasedCapitalRequiredToBeWellCapitalized" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapitalToRiskWeightedAssets" name="CommonEquityTierOneRiskBasedCapitalToRiskWeightedAssets" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" />
  <xsd:element id="ssb_CommonEquityTierOneRiskBasedCapitalRequiredToBeWellCapitalizedToRiskWeightedAssets" name="CommonEquityTierOneRiskBasedCapitalRequiredToBeWellCapitalizedToRiskWeightedAssets" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" />
  <xsd:element id="ssb_SouthStateBankMember" name="SouthStateBankMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_FairValueAdjustmentForLoansHeldForSale" name="FairValueAdjustmentForLoansHeldForSale" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_TypeOfPhasedAxis" name="TypeOfPhasedAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_TypeOfPhasedDomain" name="TypeOfPhasedDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_OtherCommercialNonOwnerOccupiedRealEstateMember" name="OtherCommercialNonOwnerOccupiedRealEstateMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_NonAcquiredCreditImpairedLoansMember" name="NonAcquiredCreditImpairedLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" abstract="true" />
  <xsd:element id="ssb_ConsumerLoansMember" name="ConsumerLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_AccruedInterestReceivableFairValueDisclosure" name="AccruedInterestReceivableFairValueDisclosure" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_AccruedInterestPayableFairValueDisclosure" name="AccruedInterestPayableFairValueDisclosure" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetServicingAssetsResultingFromTransfers" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetServicingAssetsResultingFromTransfers" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_ConsumerOwnerOccupiedLoansMember" name="ConsumerOwnerOccupiedLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_CommercialOwnerOccupiedRealEstateLoansMember" name="CommercialOwnerOccupiedRealEstateLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_OtherLoansMember" name="OtherLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_ValueOfStockIssuedPursuantToRestrictedStockUnits" name="ValueOfStockIssuedPursuantToRestrictedStockUnits" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="credit" />
  <xsd:element id="ssb_NumberOfStockIssuedPursuantToRestrictedStockUnits" name="NumberOfStockIssuedPursuantToRestrictedStockUnits" nillable="true" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ssb_MortgageServicingRightHedgingMember" name="MortgageServicingRightHedgingMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_MortgageServicingRightCommitmentsMember" name="MortgageServicingRightCommitmentsMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_OtherRealEstateWriteDowns" name="OtherRealEstateWriteDowns" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_CounterpartyMember" name="CounterpartyMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_BorrowerMember" name="BorrowerMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_OtherNonmarketableInvestmentSecuritiesMember" name="OtherNonmarketableInvestmentSecuritiesMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_PerformanceBasedRestrictedStockUnitsMember" name="PerformanceBasedRestrictedStockUnitsMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_OtherPerformanceBasedRestrictedStockUnitsMember" name="OtherPerformanceBasedRestrictedStockUnitsMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_TimedBasedRestrictedStockUnitsMember" name="TimedBasedRestrictedStockUnitsMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_DefinedContributionPlanTerminationExpense" name="DefinedContributionPlanTerminationExpense" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_DepreciationDepletionAndAmortizationOtherThanAmortizationOfDebtDiscountPremium" name="DepreciationDepletionAndAmortizationOtherThanAmortizationOfDebtDiscountPremium" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_LesseeOperatingLeasesLiabilityNotYetCommenced" name="LesseeOperatingLeasesLiabilityNotYetCommenced" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_LiabilityRecordedForExpectedCreditLossesOnUnfundedCommitments" name="LiabilityRecordedForExpectedCreditLossesOnUnfundedCommitments" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_FinancingReceivableCollateralDependentLoansTableTextBlock" name="FinancingReceivableCollateralDependentLoansTableTextBlock" nillable="true" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ssb_FinancingReceivableRecordedInvestmentCollateralDependentLoans" name="FinancingReceivableRecordedInvestmentCollateralDependentLoans" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_FinancingReceivableCollateralDependentLoansCollateralCoverage" name="FinancingReceivableCollateralDependentLoansCollateralCoverage" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_FinancingReceivableCollateralDependentLoansCollateralCoveragePercentage" name="FinancingReceivableCollateralDependentLoansCollateralCoveragePercentage" nillable="true" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ssb_AcquiredNonPurchasedCreditDeterioratedLoansMember" name="AcquiredNonPurchasedCreditDeterioratedLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_AcquiredPurchasedCreditDeterioratedLoansMember" name="AcquiredPurchasedCreditDeterioratedLoansMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_CorporateAndSubordinatedDebentures" name="CorporateAndSubordinatedDebentures" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_ReserveForUnfundedCommitments" name="ReserveForUnfundedCommitments" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_ReasonableAndSupportableForecastPeriod" name="ReasonableAndSupportableForecastPeriod" nillable="true" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ssb_CorrespondentBankingAndCapitalMarketIncomeMember" name="CorrespondentBankingAndCapitalMarketIncomeMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_FinancingReceivableRecordedInvestmentDecreaseInCollateralDependentLoans" name="FinancingReceivableRecordedInvestmentDecreaseInCollateralDependentLoans" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_IncreaseDecreaseInOperatingCashFlowChangeInAssetAndLiability" name="IncreaseDecreaseInOperatingCashFlowChangeInAssetAndLiability" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="credit" />
  <xsd:element id="ssb_ChurchMember" name="ChurchMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_RightOfUseAssetObtainedDuringPeriod" name="RightOfUseAssetObtainedDuringPeriod" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" xbrli:balance="debit" />
  <xsd:element id="ssb_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="credit" />
  <xsd:element id="ssb_FrbBorrowingsMember" name="FrbBorrowingsMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_Plan2020Member" name="Plan2020Member" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_BankPropertyHeldForSale" name="BankPropertyHeldForSale" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_TradingSecuritiesFairValue" name="TradingSecuritiesFairValue" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_SmallBusinessAdministrationLoanBackedSecuritiesMember" name="SmallBusinessAdministrationLoanBackedSecuritiesMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_ResidentialCollateralizedMortgageObligationsIssuedByU.s.GovernmentAgenciesOrSponsoredEnterprisesMember" name="ResidentialCollateralizedMortgageObligationsIssuedByU.s.GovernmentAgenciesOrSponsoredEnterprisesMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ssb_FederalFundsSoldAndInterestEarningDepositsWithBanks" name="FederalFundsSoldAndInterestEarningDepositsWithBanks" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ssb_AtlanticCapitalBancsharesIncMember" name="AtlanticCapitalBancsharesIncMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element name="StockRepurchaseProgram2021Member" id="ssb_StockRepurchaseProgram2021Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DebtSecuritiesTradingGainLossOnSaleOfSecurities" id="ssb_DebtSecuritiesTradingGainLossOnSaleOfSecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtSecuritiesTradingGainLossOnMarkToMarketSecurities" id="ssb_DebtSecuritiesTradingGainLossOnMarkToMarketSecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DebtSecuritiesAvailableForSaleSoldDuringPeriod" id="ssb_DebtSecuritiesAvailableForSaleSoldDuringPeriod" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="InterestBearingDepositLiabilitiesMember" id="ssb_InterestBearingDepositLiabilitiesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CashReceivedAsCollateralForDerivativeInstruments" id="ssb_CashReceivedAsCollateralForDerivativeInstruments" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationQuarterOne" id="ssb_FiniteLivedIntangibleAssetExpectedAmortizationQuarterOne" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationQuarterTwo" id="ssb_FiniteLivedIntangibleAssetExpectedAmortizationQuarterTwo" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationQuarterThree" id="ssb_FiniteLivedIntangibleAssetExpectedAmortizationQuarterThree" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationQuarterFour" id="ssb_FiniteLivedIntangibleAssetExpectedAmortizationQuarterFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationQuarterFive" id="ssb_FiniteLivedIntangibleAssetExpectedAmortizationQuarterFive" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FiniteLivedIntangibleAssetExpectedAmortizationAfterQuarterFive" id="ssb_FiniteLivedIntangibleAssetExpectedAmortizationAfterQuarterFive" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PhasingOutPercentage" id="ssb_PhasingOutPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SmallBusinessAdministrationIncomeMember" id="ssb_SmallBusinessAdministrationIncomeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SmallBusinessAdministrationServicingAssetsFairValueDisclosure" id="ssb_SmallBusinessAdministrationServicingAssetsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="StockRepurchaseProgram2022Member" id="ssb_StockRepurchaseProgram2022Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OtherIntangibleAssetsExcludingSmallBusinessAdministrationServicingAssetsMember" id="ssb_OtherIntangibleAssetsExcludingSmallBusinessAdministrationServicingAssetsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancingReceivableIndividualQuantitativeImpairment" id="ssb_FinancingReceivableIndividualQuantitativeImpairment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtSecuritiesHeldToMaturityContinuousUnrealizedLossPosition12MonthsOrLongerGrossUnrealizedLoss" id="ssb_DebtSecuritiesHeldToMaturityContinuousUnrealizedLossPosition12MonthsOrLongerGrossUnrealizedLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtSecuritiesHeldToMaturityContinuousUnrealizedLossPosition12MonthsOrLongerFairValueDisclosure" id="ssb_DebtSecuritiesHeldToMaturityContinuousUnrealizedLossPosition12MonthsOrLongerFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtSecuritiesHeldToMaturityUnrealizedLossPositionAccumulatedLossesAbstract" id="ssb_DebtSecuritiesHeldToMaturityUnrealizedLossPositionAccumulatedLossesAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DebtSecuritiesHeldToMaturityContinuousUnrealizedLossPositionFairValueDisclosureAbstract" id="ssb_DebtSecuritiesHeldToMaturityContinuousUnrealizedLossPositionFairValueDisclosureAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MortgageServicingRightsMember" id="ssb_MortgageServicingRightsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ReductionInDerivativeAssetFairValue" id="ssb_ReductionInDerivativeAssetFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SbaServicingRightsMember" id="ssb_SbaServicingRightsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CorporateAndSubordinatedDebenturesFairValueDisclosure" id="ssb_CorporateAndSubordinatedDebenturesFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="OtherDerivativeFinancialInstrumentsFairValue" id="ssb_OtherDerivativeFinancialInstrumentsFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CashPledgedAsCollateral" id="ssb_CashPledgedAsCollateral" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FinancingReceivableModificationsAccruedInterestReceivable" id="ssb_FinancingReceivableModificationsAccruedInterestReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ScheduleOfMortgageLoansHeldForSaleTableTextBlock" id="ssb_ScheduleOfMortgageLoansHeldForSaleTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="LoanMortgageHeldForSaleUnpaidPrincipalBalance" id="ssb_LoanMortgageHeldForSaleUnpaidPrincipalBalance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LoanMortgageHeldForSaleFairValueAfterUnpaidPrincipalBalance" id="ssb_LoanMortgageHeldForSaleFairValueAfterUnpaidPrincipalBalance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="NoninterestBearingDepositsFairValueDisclosure" id="ssb_NoninterestBearingDepositsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="NoninterestBearingOtherThanTimeDepositsFairValueDisclosure" id="ssb_NoninterestBearingOtherThanTimeDepositsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="TimeDepositsFairValueDisclosure" id="ssb_TimeDepositsFairValueDisclosure" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LoansHeldForSaleLossReimbursementAndSettlementPaid" id="ssb_LoansHeldForSaleLossReimbursementAndSettlementPaid" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="BankingRegulationTier1RiskBasedCapitalRatioCapitalAdequacyWithBufferMinimum" id="ssb_BankingRegulationTier1RiskBasedCapitalRatioCapitalAdequacyWithBufferMinimum" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="BankingRegulationTier1RiskBasedCapitalCapitalAdequacyWithBufferMinimum" id="ssb_BankingRegulationTier1RiskBasedCapitalCapitalAdequacyWithBufferMinimum" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LoansRepurchasedAndAggregatedPrincipalBalances" id="ssb_LoansRepurchasedAndAggregatedPrincipalBalances" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="TermExtensionAndInterestRateReductionMember" id="ssb_TermExtensionAndInterestRateReductionMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancingReceivableModificationAmortizedCostUnderRestructuredTerms" id="ssb_FinancingReceivableModificationAmortizedCostUnderRestructuredTerms" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FederalDepositInsuranceCorporationSpecialAssessmentExpense" id="ssb_FederalDepositInsuranceCorporationSpecialAssessmentExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="UninsuredDepositsBaseAnnualRate" id="ssb_UninsuredDepositsBaseAnnualRate" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AmountOfUninsuredDepositsAdjustedToExclude" id="ssb_AmountOfUninsuredDepositsAdjustedToExclude" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SpecialAssessmentPeriod" id="ssb_SpecialAssessmentPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="FdicSpecialAssessment" id="ssb_FdicSpecialAssessment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="NetBookBalanceForNonAccrualLoanToBeEvaluatedIndividuallyForLoss" id="ssb_NetBookBalanceForNonAccrualLoanToBeEvaluatedIndividuallyForLoss" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeaseInitialDirectCosts" id="ssb_DirectFinancingLeaseInitialDirectCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeaseUnearnedIncome" id="ssb_DirectFinancingLeaseUnearnedIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedFiscalYearMaturityAbstract" id="ssb_DirectFinancingLeasesPaymentToBeReceivedFiscalYearMaturityAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedYearOne" id="ssb_DirectFinancingLeasesPaymentToBeReceivedYearOne" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedYearTwo" id="ssb_DirectFinancingLeasesPaymentToBeReceivedYearTwo" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedYearThree" id="ssb_DirectFinancingLeasesPaymentToBeReceivedYearThree" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedYearFour" id="ssb_DirectFinancingLeasesPaymentToBeReceivedYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceived" id="ssb_DirectFinancingLeasesPaymentToBeReceived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesLeaseReceivableUndiscountedExcessAmount" id="ssb_DirectFinancingLeasesLeaseReceivableUndiscountedExcessAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ScheduleOfLeaseReceivablesAndInvestmentInOperatingLeasesAndTheirCorrespondingBalanceSheetLocationTableTextBlock" id="ssb_ScheduleOfLeaseReceivablesAndInvestmentInOperatingLeasesAndTheirCorrespondingBalanceSheetLocationTableTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="BalanceSheetFairValueHedgeLoansHedgedItemAmortizedCostBasis" id="ssb_BalanceSheetFairValueHedgeLoansHedgedItemAmortizedCostBasis" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseIncreaseInPrepaymentSpeed" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseIncreaseInPrepaymentSpeed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseDecreaseInPrepaymentSpeed" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseDecreaseInPrepaymentSpeed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseIncreaseInPrepaymentSpeed" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseIncreaseInPrepaymentSpeed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseDecreaseInPrepaymentSpeed" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseDecreaseInPrepaymentSpeed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseIncreaseInDiscountRate" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseIncreaseInDiscountRate" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseDecreaseInDiscountRate" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf10PercentAdverseDecreaseInDiscountRate" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseIncreaseInDiscountRate" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseIncreaseInDiscountRate" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseDecreaseInDiscountRate" id="ssb_SensitivityAnalysisOfFairValueTransferorSInterestsInTransferredFinancialAssetsImpactOf20PercentAdverseDecreaseInDiscountRate" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedRemainderOfFiscalYear" id="ssb_DirectFinancingLeasesPaymentToBeReceivedRemainderOfFiscalYear" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DirectFinancingLeasesPaymentToBeReceivedAfterYearFour" id="ssb_DirectFinancingLeasesPaymentToBeReceivedAfterYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="Plan2004And2012Or2019Member" id="ssb_Plan2004And2012Or2019Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TwoThousandTwentyOneAndTwoThousandTwentyTwoAndTwoThousandTwentyThreeLtiPerformanceBasedRsuGrantsMember" id="ssb_TwoThousandTwentyOneAndTwoThousandTwentyTwoAndTwoThousandTwentyThreeLtiPerformanceBasedRsuGrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AdjustmentToRetainedEarningsForDeferredTaxes" id="ssb_AdjustmentToRetainedEarningsForDeferredTaxes" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PercentageOfRemainingFundingObligationExpectedToBeFunded" id="ssb_PercentageOfRemainingFundingObligationExpectedToBeFunded" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="FederalDepositInsuranceCorporationSpecialAssessmentAdditionalExpense" id="ssb_FederalDepositInsuranceCorporationSpecialAssessmentAdditionalExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="CommonEquityTierOneRiskBasedCapitalRequiredForCapitalAdequacy" id="ssb_CommonEquityTierOneRiskBasedCapitalRequiredForCapitalAdequacy" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="FinancialServiceProductOneMember" id="ssb_FinancialServiceProductOneMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductTwoMember" id="ssb_FinancialServiceProductTwoMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductThreeMember" id="ssb_FinancialServiceProductThreeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductFourMember" id="ssb_FinancialServiceProductFourMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductFiveMember" id="ssb_FinancialServiceProductFiveMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductSixMember" id="ssb_FinancialServiceProductSixMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductSevenMember" id="ssb_FinancialServiceProductSevenMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductEightMember" id="ssb_FinancialServiceProductEightMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductNineMember" id="ssb_FinancialServiceProductNineMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductTenMember" id="ssb_FinancialServiceProductTenMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="FinancialServiceProductElevenMember" id="ssb_FinancialServiceProductElevenMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="O2024Q3DividendsMember" id="ssb_O2024Q3DividendsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OneToFourFamilyInvestmentPropertyMember" id="ssb_OneToFourFamilyInvestmentPropertyMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TermExtensionAndPaymentDelayMember" id="ssb_TermExtensionAndPaymentDelayMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PaymentForOriginationAndPurchaseLoanMortgageHeldForSale" id="ssb_PaymentForOriginationAndPurchaseLoanMortgageHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PaymentForOriginationAndPurchaseLoanSmallBusinessAdministrationHeldForSale" id="ssb_PaymentForOriginationAndPurchaseLoanSmallBusinessAdministrationHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromSaleLoanSmallBusinessAdministrationHeldForSale" id="ssb_ProceedsFromSaleLoanSmallBusinessAdministrationHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="GainLossOnSaleOfSmallBusinessAdministrationLoansHeldForSale" id="ssb_GainLossOnSaleOfSmallBusinessAdministrationLoansHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PoolingOfSmallBusinessAdministrationLoansHeldForSale" id="ssb_PoolingOfSmallBusinessAdministrationLoansHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SmallBusinessAdministrationLoansHeldForSaleDisclosuresAbstract" id="ssb_SmallBusinessAdministrationLoansHeldForSaleDisclosuresAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SmallBusinessAdministrationLoansHeldForSaleDisclosuresTextBlock" id="ssb_SmallBusinessAdministrationLoansHeldForSaleDisclosuresTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PaymentForPurchaseGuaranteedPortionOfLoanSmallBusinessAdministrationHeldForSale" id="ssb_PaymentForPurchaseGuaranteedPortionOfLoanSmallBusinessAdministrationHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ProceedsFromSaleOfSmallBusinessAdministrationLoansSecondaryMarket" id="ssb_ProceedsFromSaleOfSmallBusinessAdministrationLoansSecondaryMarket" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProceedsFromSaleOfIndividualSmallBusinessAdministrationLoans" id="ssb_ProceedsFromSaleOfIndividualSmallBusinessAdministrationLoans" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ProceedsFromSaleGuaranteedPortionOfLoanSmallBusinessAdministrationHeldForSale" id="ssb_ProceedsFromSaleGuaranteedPortionOfLoanSmallBusinessAdministrationHeldForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
</xsd:schema>
