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Organization and Significant Accounting Policies, Property, Plant and Equipment (Details) - USD ($) $ in Thousands | 12 Months Ended |
--- | --- | ---
Dec. 31, 2018 | Dec. 31, 2017
Property, Plant and Equipment [Abstract] |  |
Less accumulated depreciation | $ (61,474) | $ (87,676)
Property, plant and equipment, net | 132,160 | 121,907
Property, Plant and Equipment, Excluding Land [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | 179,141 | 195,090
Property, plant and equipment, net | 117,667 | 107,414
Computer Software, Laboratory, Manufacturing and Other Equipment [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | $ 53,496 | 66,558
Computer Software, Laboratory, Manufacturing and Other Equipment [Member] | Minimum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 3 years |
Computer Software, Laboratory, Manufacturing and Other Equipment [Member] | Maximum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 10 years |
Building, Building Improvements and Building Systems [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | $ 97,528 | 92,770
Building, Building Improvements and Building Systems [Member] | Minimum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 15 years |
Building, Building Improvements and Building Systems [Member] | Maximum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 40 years |
Land Improvements [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | $ 2,853 | 2,853
Estimated useful lives | 20 years |
Leasehold Improvements [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | $ 18,981 | 26,748
Leasehold Improvements [Member] | Minimum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 5 years |
Leasehold Improvements [Member] | Maximum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 15 years |
Furniture and Fixtures [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | $ 6,283 | 6,161
Furniture and Fixtures [Member] | Minimum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 5 years |
Furniture and Fixtures [Member] | Maximum [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Estimated useful lives | 10 years |
Land [Member] |  |
Property, Plant and Equipment [Abstract] |  |
Property, plant and equipment | $ 14,493 | $ 14,493

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- Definition Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.13) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- Definition Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment. + References No definition available. + Details
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