# Filing Detail

Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]:
SEC Accession No. 0000874015-19-000045
Filing Date
2019-03-01
Accepted
2019-03-01 14:39:05
Documents
121
Period of Report
2018-12-31

Document Format Files

Seq | Description | Document | Type | Size
--- | --- | --- | --- | ---
1 | IONIS PHARMACEUTICALS INC 10-K 12-31-2018 | form10k.htm | 10-K | 3911614
2 | EXHIBIT 10.67 | exhibit10_67.htm | EX-10.67 | 788281
3 | EXHIBIT 10.68 | exhibit10_68.htm | EX-10.68 | 2174149
4 | EXHIBIT 10.69 | exhibit10_69.htm | EX-10.69 | 22224
5 | EXHIBIT 10.70 | exhibit10_70.htm | EX-10.70 | 24629
6 | EXHIBIT 21.1 | exhibit21_1.htm | EX-21.1 | 5005
7 | EXHIBIT 23.1 | exhibit23_1.htm | EX-23.1 | 4594
8 | EXHIBIT 31.1 | exhibit31_1.htm | EX-31.1 | 15128
9 | EXHIBIT 31.2 | exhibit31_2.htm | EX-31.2 | 15121
10 | EXHIBIT 32.1 | exhibit32_1.htm | EX-32 | 8951
17 |  | image01.jpg | GRAPHIC | 182632
18 |  | image02.jpg | GRAPHIC | 16613
19 |  | image03.jpg | GRAPHIC | 55172
20 |  | image04.jpg | GRAPHIC | 55354
21 |  | image05.jpg | GRAPHIC | 38873
22 |  | image06.jpg | GRAPHIC | 86177
23 |  | image07.jpg | GRAPHIC | 50048
24 |  | image08.jpg | GRAPHIC | 95827
25 |  | image09.jpg | GRAPHIC | 55377
26 |  | image10.jpg | GRAPHIC | 46106
27 |  | image11.jpg | GRAPHIC | 91400
28 |  | image12.jpg | GRAPHIC | 31669
29 |  | image13.jpg | GRAPHIC | 25608
30 |  | image14.jpg | GRAPHIC | 24762
31 |  | image15.jpg | GRAPHIC | 112488
32 |  | image16.jpg | GRAPHIC | 34560
| Complete submission text file | 0000874015-19-000045.txt |  | 23067663

Data Files

Seq | Description | Document | Type | Size
--- | --- | --- | --- | ---
11 | XBRL INSTANCE DOCUMENT | ions-20181231.xml | EX-101.INS | 4406129
12 | XBRL TAXONOMY EXTENSION SCHEMA | ions-20181231.xsd | EX-101.SCH | 108872
13 | XBRL TAXONOMY EXTENSION CALCULATION LINKBASE | ions-20181231_cal.xml | EX-101.CAL | 139137
14 | XBRL TAXONOMY EXTENSION DEFINITION LINKBASE | ions-20181231_def.xml | EX-101.DEF | 797209
15 | XBRL TAXONOMY EXTENSION LABEL LINKBASE | ions-20181231_lab.xml | EX-101.LAB | 1596582
16 | XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE | ions-20181231_pre.xml | EX-101.PRE | 1020079

Mailing Address 2855 GAZELLE COURT CARLSBAD CA 92010
Business Address 2855 GAZELLE COURT CARLSBAD CA 92010 7609319200
IONIS PHARMACEUTICALS INC (Filer) CIK: 0000874015 (see all company filings)

EIN.: 330336973 | State of Incorp.: DE | Fiscal Year End: 1231
Type: 10-K | Act: 34 | File No.: 000-19125 | Film No.: 19648494
SIC: 2834 Pharmaceutical Preparations