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v3.22.1

Collaborative Arrangements and Licensing Agreements (Details) $ in Thousands | 3 Months Ended |
--- | --- | ---
Mar. 31, 2022 USD ($) Target | Jun. 30, 2021 USD ($) | Mar. 31, 2021 USD ($) | Dec. 31, 2021 USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue | $ 141,919 |  | $ 111,607 |
SPINRAZA Royalties [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue | 53,818 |  | 59,986 |
R&D Revenue [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue | 69,634 |  | 27,159 |
Biogen [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Cumulative payments received | 3,300,000 |  |  |
Revenue | 93,900 |  | $ 78,100 |
Deferred revenue | $ 385,500 |  |  | $ 407,500
Biogen [Member] | Revenue [Member] | Strategic Partner [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Concentration percentage | 66.00% |  | 70.00% |
Biogen [Member] | SPINRAZA Royalties [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue | $ 53,800 |  | $ 60,000 |
Biogen [Member] | R&D Revenue [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue | 40,100 |  | $ 18,100 |
2013 Strategic Neurology [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue | $ 18,000 |  |  |
Number of targets advanced | Target | 2 |  |  |
2013 Strategic Neurology [Member] | ION541 [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Revenue |  | $ 18,000 |  |
2013 Strategic Neurology [Member] | Maximum [Member] |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |
Next prospective payment | $ 10,000 |  |  |

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