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v3.22.1

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Operating activities: |  |
Net loss | $ (65,165) | $ (89,869)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 3,701 | 3,917
Amortization of right-of-use operating lease assets | 602 | 394
Amortization of patents | 592 | 544
Amortization of premium on investments, net | 4,175 | 4,023
Amortization of debt issuance costs | 1,343 | 860
Stock-based compensation expense | 26,236 | 37,861
Gain on investments | (10) | (13)
Non-cash losses related to disposal of property, plant and equipment | 527 | 0
Non-cash losses related to patents | 110 | 221
Changes in operating assets and liabilities: |  |
Contracts receivable | 35,774 | 52,807
Inventories | 774 | (234)
Other current and long-term assets | (7,222) | 16,481
Income taxes receivable | 865 | 2
Accounts payable | 2,878 | (9,569)
Accrued compensation | (22,285) | (36,465)
Accrued liabilities and other current liabilities | 10,473 | (11,905)
Deferred contract revenue | (25,018) | (23,717)
Net cash used in operating activities | (31,650) | (54,662)
Investing activities: |  |
Purchases of short-term investments | (462,855) | (330,051)
Proceeds from sale of short-term investments | 178,837 | 411,907
Purchases of property, plant and equipment | (2,705) | (1,772)
Acquisition of licenses and other assets, net | (826) | (1,228)
Net cash (used in) provided by investing activities | (287,549) | 78,856
Financing activities: |  |
Proceeds from equity, net | 1,848 | 7,760
Payments of tax withholdings related to vesting of employee stock awards and exercise of employee stock options | (9,173) | (15,337)
Net cash used in financing activities | (7,325) | (7,577)
Effects of exchange rates on cash | (154) | (126)
Net (decrease) increase in cash and cash equivalents | (326,678) | 16,491
Cash and cash equivalents at beginning of period | 869,191 | 397,664
Cash and cash equivalents at end of period | 542,513 | 414,155
Supplemental disclosures of cash flow information: |  |
Interest paid | 594 | 594
Income taxes paid | 2 | 2
Supplemental disclosures of non-cash investing and financing activities: |  |
Amounts accrued for capital and patent expenditures | $ 1,344 | $ 1,876

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