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Collaborative Arrangements and Licensing Agreements, Biogen (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Jul. 31, 2022 USD ($) | Jun. 30, 2022 USD ($) | Mar. 31, 2022 USD ($) Target | Jun. 30, 2021 USD ($) | Jun. 30, 2022 USD ($) | Jun. 30, 2021 USD ($) | Dec. 31, 2021 USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue |  | $ 133,791 |  | $ 125,750 | $ 275,710 | $ 237,357 |
SPINRAZA Royalties [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue |  | 59,627 |  | 72,168 | 113,444 | 132,154 |
R&D Revenue [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue |  | 55,607 |  | 39,889 | 125,242 | 67,048 |
Biogen [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Cumulative payments received |  | 3,300,000 |  |  | 3,300,000 |  |
Revenue |  | 76,900 |  | $ 100,000 | 170,800 | $ 178,100 |
Deferred revenue |  | $ 368,300 |  |  | $ 368,300 |  | $ 407,500
Biogen [Member] | Revenue [Member] | Strategic Partner [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Concentration percentage |  | 58.00% |  | 80.00% | 62.00% | 75.00% |
Biogen [Member] | SPINRAZA Royalties [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue |  | $ 59,600 |  | $ 72,200 | $ 113,400 | $ 132,200 |
Biogen [Member] | R&D Revenue [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue |  | $ 17,300 |  | $ 27,800 | $ 57,400 | $ 45,900 |
2013 Strategic Neurology [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue |  |  | $ 18,000 |  |  |  |
Number of targets advanced | Target |  |  | 2 |  |  |  |
2013 Strategic Neurology [Member] | Subsequent Event [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Revenue | $ 9,000 |  |  |  |  |  |
2013 Strategic Neurology [Member] | Maximum [Member] | Plan [Member] |  |  |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |  |  |
Next prospective payment | $ 10,000 |  |  |  |  |  |

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