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Legal Proceedings (Details) - John Makris, et al. v. Ionis Pharmaceuticals, Inc., et al. [Member] $ in Millions |  | 1 Months Ended | 3 Months Ended | 6 Months Ended
--- | --- | --- | --- | ---
Aug. 05, 2021 Plaintiff | Jul. 31, 2022 USD ($) | Jun. 30, 2022 USD ($) | Jun. 30, 2022 USD ($)
Legal Procedings [Abstract] |  |  |  |
Number of plaintiffs | Plaintiff | 4 |  |  |
Legal reserve for proposed litigation settlement |  |  | $ 12.5 | $ 12.5
Subsequent Event [Member] |  |  |  |
Legal Procedings [Abstract] |  |  |  |
Contribution to settlement agreement by insurance carrier |  | $ 4.5 |  |
Other Expense [Member] |  |  |  |
Legal Procedings [Abstract] |  |  |  |
Litigation settlement expense |  |  | $ 12.5 | $ 12.5

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