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Collaborative Arrangements and Licensing Agreements, Bayer (Details) $ in Millions | Sep. 30, 2022 USD ($)
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Bayer Collaboration [Member] |
Collaborative Arrangement and Licensing Agreement [Abstract] |
Cumulative payments received | $ 190

X
- References No definition available. + Details
Name: | ions_CollaborativeArrangementAndLicensingAgreementAbstract
Namespace Prefix: | ions_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Cumulative amount of payments received under the collaboration agreement as of the end of the reporting period. + References No definition available. + Details
Name: | ions_CumulativePaymentsReceived
Namespace Prefix: | ions_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

X
- Details
Name: | us-gaap_TypeOfArrangementAxis=ions_BayerCollaborationIonisFxiMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |