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Collaborative Arrangements and Licensing Agreements, Biogen (Details) $ in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2022 USD ($) Payment Target | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Dec. 31, 2021 USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Revenue | $ 159,767 | $ 133,093 | $ 435,478 | $ 370,450 |
SPINRAZA Royalties [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Revenue | 61,647 | 66,572 | 175,092 | 198,726 |
R&D Revenue [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Revenue | 87,357 | 48,273 | 212,599 | 115,321 |
Biogen Collaborations [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Cumulative payments received | 3,400,000 |  | 3,400,000 |  |
Revenue | 89,000 | $ 84,000 | 259,700 | $ 262,100 |
Deferred revenue | $ 360,200 |  | $ 360,200 |  | $ 407,500
Biogen Collaborations [Member] | Revenue [Member] | Strategic Partner [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Concentration percentage | 56.00% | 63.00% | 60.00% | 71.00% |
Biogen Collaborations [Member] | SPINRAZA Royalties [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Revenue | $ 61,600 | $ 66,600 | $ 175,100 | $ 198,700 |
Biogen Collaborations [Member] | R&D Revenue [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Revenue | 27,400 | $ 17,400 | 84,600 | $ 63,400 |
Neurology Collaborations with Biogen [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Revenue | $ 13,000 |  |  |  |
Number of targets advanced | Target | 2 |  |  |  |
Number of milestone payments recognized in full | Payment | 1 |  |  |  |
2013 Strategic Neurology Collaboration with Biogen [Member] | Maximum [Member] |  |  |  |  |
Collaborative Arrangement and Licensing Agreement [Abstract] |  |  |  |  |
Next prospective payment | $ 10,000 |  | $ 10,000 |  |

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