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Organization and Significant Accounting Policies, Property, Plant and Equipment (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Oct. 31, 2022 | Dec. 31, 2022 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Property, Plant and Equipment [Abstract] |  |  |  |  |
Less accumulated depreciation |  | $ (87,716) | $ (87,716) | $ (102,653) |
Property, plant and equipment, net |  | 74,294 | 74,294 | 178,069 |
Net proceeds from sale of real estate assets | $ 202,600 |  |  |  |
Gain on sale of real estate assets |  | 150,100 | 150,135 | 0 | $ 0
Property, Plant and Equipment, Excluding Land [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Property, plant and equipment |  | 153,441 | 153,441 | 257,660 |
Property, plant and equipment, net |  | 65,725 | 65,725 | 155,007 |
Computer Software, Laboratory, Manufacturing and Other Equipment [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Property, plant and equipment |  | 74,351 | $ 74,351 | 72,802 |
Computer Software, Laboratory, Manufacturing and Other Equipment [Member] | Minimum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 3 years |  |
Computer Software, Laboratory, Manufacturing and Other Equipment [Member] | Maximum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 10 years |  |
Building, Building Improvements and Building Systems [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Property, plant and equipment |  | 41,158 | $ 41,158 | 144,046 |
Building, Building Improvements and Building Systems [Member] | Minimum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 15 years |  |
Building, Building Improvements and Building Systems [Member] | Maximum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 40 years |  |
Land Improvements [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 20 years |  |
Property, plant and equipment |  | 0 | $ 0 | 10,077 |
Leasehold Improvements [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Property, plant and equipment |  | 28,357 | $ 28,357 | 20,144 |
Leasehold Improvements [Member] | Minimum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 5 years |  |
Leasehold Improvements [Member] | Maximum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 15 years |  |
Furniture and Fixtures [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Property, plant and equipment |  | 9,575 | $ 9,575 | 10,591 |
Furniture and Fixtures [Member] | Minimum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 5 years |  |
Furniture and Fixtures [Member] | Maximum [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Estimated useful life |  |  | 10 years |  |
Land [Member] |  |  |  |  |
Property, Plant and Equipment [Abstract] |  |  |  |  |
Property, plant and equipment |  | $ 8,569 | $ 8,569 | $ 23,062 |

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