# Filing Detail

Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]:
SEC Accession No. 0000874015-23-000105
Filing Date
2023-02-22
Accepted
2023-02-22 16:39:54
Documents
123
Period of Report
2022-12-31

Document Format Files

Seq | Description | Document | Type | Size
--- | --- | --- | --- | ---
1 | IONIS PHARMACEUTICALS, INC. 10-K 12-31-2022 | form10k.htm iXBRL | 10-K | 3560963
2 | EXHIBIT 10.1 | exhibit10-10.htm | EX-10.10 | 39692
3 | EXHIBIT 10.13 | exhibit10-13.htm | EX-10.13 | 31608
4 | EXHIBIT 10.14 | exhibit10-14.htm | EX-10.14 | 55999
5 | EXHIBIT 10.16 | exhibit10-16.htm | EX-10.16 | 84781
6 | EXHIBIT 10.23 | exhibit10-23.htm | EX-10.23 | 1142713
7 | EXHIBIT 10.24 | exhibit10-24.htm | EX-10.24 | 1309936
8 | EXHIBIT 10.25 | exhibit10-25.htm | EX-10.25 | 1622453
9 | EXHIBIT 10.26 | exhibit10-26.htm | EX-10.26 | 826479
10 | EXHIBIT 10.27 | exhibit10-27.htm | EX-10.27 | 307488
11 | EXHIBIT 10.28 | exhibit10-28.htm | EX-10.28 | 139887
12 | EXHIBIT 10.29 | exhibit10-29.htm | EX-10.29 | 148517
13 | EXHIBIT 10.80 | exhibit10-80.htm | EX-10.80 | 971167
14 | EXHIBIT 10.81 | exhibit10-81.htm | EX-10.81 | 324684
15 | EXHIBIT 14 | exhibit14.htm | EX-14 | 100962
16 | EXHIBIT 21.1 | exhibit21-1.htm | EX-21.1 | 4088
17 | EXHIBIT 23.1 | exhibit23-1.htm | EX-23.1 | 3312
18 | EXHIBIT 31.1 | exhibit31-1.htm | EX-31.1 | 12635
19 | EXHIBIT 31.2 | exhibit31-2.htm | EX-31.2 | 12643
20 | EXHIBIT 32.1 | exhibit32-1.htm | EX-32 | 7291
26 |  | image0.jpg | GRAPHIC | 168742
27 |  | image1.jpg | GRAPHIC | 34761
28 |  | image2.jpg | GRAPHIC | 131783
29 |  | image3.jpg | GRAPHIC | 113867
30 |  | image4.jpg | GRAPHIC | 94751
31 |  | image5.jpg | GRAPHIC | 33280
32 |  | image6.jpg | GRAPHIC | 53438
33 |  | image07.jpg | GRAPHIC | 4712
34 |  | image7.jpg | GRAPHIC | 112488
35 |  | image8.jpg | GRAPHIC | 30818
36 |  | image11.jpg | GRAPHIC | 5123
| Complete submission text file | 0000874015-23-000105.txt |  | 26887667

Data Files

Seq | Description | Document | Type | Size
--- | --- | --- | --- | ---
21 | XBRL TAXONOMY EXTENSION SCHEMA | ions-20221231.xsd | EX-101.SCH | 105455
22 | XBRL TAXONOMY EXTENSION CALCULATION LINKBASE | ions-20221231_cal.xml | EX-101.CAL | 149259
23 | XBRL TAXONOMY EXTENSION DEFINITION LINKBASE | ions-20221231_def.xml | EX-101.DEF | 684528
24 | XBRL TAXONOMY EXTENSION LABEL LINKBASE | ions-20221231_lab.xml | EX-101.LAB | 1598235
25 | XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE | ions-20221231_pre.xml | EX-101.PRE | 944165
117 | EXTRACTED XBRL INSTANCE DOCUMENT | form10k_htm.xml | XML | 2892042

Mailing Address 2855 GAZELLE COURT CARLSBAD CA 92010
Business Address 2855 GAZELLE COURT CARLSBAD CA 92010 7609319200
IONIS PHARMACEUTICALS INC (Filer) CIK: 0000874015 (see all company filings)

EIN.: 330336973 | State of Incorp.: CA | Fiscal Year End: 1231
Type: 10-K | Act: 34 | File No.: 000-19125 | Film No.: 23653896
SIC: 2834 Pharmaceutical Preparations