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Long-Term Obligations and Commitments, Operating Leases (Details) $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2022 Lease | Jan. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) Option Lot | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($)
Operating Leases [Abstract] |  |  |  |  |
Lease payments to be made over initial term of lease |  |  | $ 299,594 |  |
Right-of-use operating lease assets |  |  | 181,544 | $ 17,974 |
Operating lease liabilities |  |  | $ 186,156 | 22,058 |
Weighted average remaining lease term |  |  | 13 years 9 months 18 days |  |
Weighted average discount rate |  |  | 6.90% |  |
Operating lease cash payments |  |  | $ 4,000 | $ 3,300 | $ 3,800
Carlsbad Facility [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Number of options to extend lease | Option |  |  | 1 |  |
Term of lease extension |  |  | 5 years |  |
Carlsbad Office Spaces [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Number of leases that were extended | Lease | 1 |  |  |  |
Number of options to extend lease | Option |  |  | 0 |  |
Headquarters Location in Carlsbad, California [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Initial term of operating lease |  |  | 15 years |  |
Number of options to extend lease | Option |  |  | 2 |  |
Term of lease extension |  |  | 5 years |  |
Lease payments to be made over initial term of lease |  |  | $ 280,000 |  |
Number of lots of undeveloped land included in purchase and sale agreement | Lot |  |  | 2 |  |
Development Chemistry and Manufacturing Facility in Oceanside, California [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Initial term of operating lease |  |  | 20 years 3 months |  |
Number of options to extend lease | Option |  |  | 2 |  |
Term of lease extension |  |  | 10 years |  |
Boston Office Space [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Initial term of operating lease |  |  | 123 months |  |
Term of lease extension |  |  | 5 years |  |
Period of free rent under lease |  |  | 3 months |  |
Subleased Office Space in Boston [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Term of sublease |  | 83 months |  |  |
Period of free rent under sublease |  | 7 months |  |  |
Lease payments to be received over term of sublease |  | $ 9,600 |  |  |
Another Office Space in Boston [Member] |  |  |  |  |
Operating Leases [Abstract] |  |  |  |  |
Initial term of operating lease |  |  | 91 months |  |
Number of options to extend lease | Option |  |  | 1 |  |
Term of lease extension |  |  | 5 years |  |
Period of free rent under lease |  |  | 7 months |  |
Lease payments to be made over initial term of lease |  |  | $ 6,800 |  |

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