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v3.23.1

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2023 | Mar. 31, 2022
Operating activities: |  |
Net loss | $ (124,323) | $ (65,165)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 2,604 | 3,701
Amortization of right-of-use operating lease assets | 2,395 | 602
Amortization of other assets | 607 | 592
Amortization of premium (discount) on investments, net | (5,042) | 4,175
Amortization of debt issuance costs | 1,486 | 1,343
Non-cash interest related to sale of future royalties | 15,363 | 0
Stock-based compensation expense | 26,948 | 26,236
Loss (gain) on investments | 529 | (10)
Non-cash losses related to disposal of property, plant and equipment | 0 | 527
Non-cash losses related to other assets | 445 | 110
Changes in operating assets and liabilities: |  |
Contracts receivable | 11,624 | 35,774
Inventories | (167) | 774
Other current and long-term assets | 5,312 | (7,222)
Income taxes payable | 11,037 | 865
Accounts payable | (10,295) | 2,878
Accrued compensation | (31,018) | (22,285)
Accrued liabilities and other current liabilities | (28,460) | 10,473
Deferred contract revenue | (13,037) | (25,018)
Net cash used in operating activities | (133,992) | (31,650)
Investing activities: |  |
Purchases of short-term investments | (688,278) | (462,855)
Proceeds from sale of short-term investments | 374,363 | 178,837
Purchases of property, plant and equipment | (10,472) | (2,705)
Acquisition of licenses and other assets, net | (1,253) | (826)
Net cash used in investing activities | (325,640) | (287,549)
Financing activities: |  |
Proceeds from equity, net | 2,560 | 1,848
Payments of tax withholdings related to vesting of employee stock awards and exercise of employee stock options | 0 | (9,173)
Proceeds from sale of future royalties | 500,000 | 0
Payments of transaction costs related to sale of future royalties | (10,434) | 0
Principal payments on mortgage debt | (39) | 0
Net cash provided by (used in) financing activities | 492,087 | (7,325)
Effects of exchange rates on cash | 104 | (154)
Net increase (decrease) in cash and cash equivalents | 32,559 | (326,678)
Cash and cash equivalents at beginning of period | 276,472 | 869,191
Cash and cash equivalents at end of period | 309,031 | 542,513
Supplemental disclosures of cash flow information: |  |
Interest paid | 89 | 594
Income taxes paid | 293 | 2
Supplemental disclosures of non-cash investing and financing activities: |  |
Amounts accrued for capital and patent expenditures | $ 3,058 | $ 1,344

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- Definition The cash outflow paid to third parties for transaction costs in connection with a monetization transaction of future SPINRAZA and pelacarsen royalties the Company is entitled to under collaboration and licensing agreements. + References No definition available. + Details
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