<SEC-DOCUMENT>0000048532-23-000002-index.html : 20230522
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<ACCEPTANCE-DATETIME>20230522150340
ACCESSION NUMBER:		0000048532-23-000002
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230522
DATE AS OF CHANGE:		20230522

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IONIS PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000874015
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				330336973
		STATE OF INCORPORATION:			CA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	000-19125
		FILM NUMBER:		23944097

	BUSINESS ADDRESS:	
		STREET 1:		2855 GAZELLE COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92010
		BUSINESS PHONE:		7609319200

	MAIL ADDRESS:	
		STREET 1:		2855 GAZELLE COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92010

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ISIS PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19930328

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INSIGHT SECURITIES, INC.
		CENTRAL INDEX KEY:			0000048532
		IRS NUMBER:				362708269
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		144

	BUSINESS ADDRESS:	
		STREET 1:		600 CENTRAL AVE
		STREET 2:		SUITE 293
		CITY:			HIGHLAND PARK
		STATE:			IL
		ZIP:			60035
		BUSINESS PHONE:		224-632-4700

	MAIL ADDRESS:	
		STREET 1:		600 CENTRAL AVE
		STREET 2:		SUITE 265
		CITY:			HIGHLAND PARK
		STATE:			IL
		ZIP:			60035

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HORWITZ & ASSOCIATES, INC.
		DATE OF NAME CHANGE:	20140102

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INSIGHT SECURITIES, INC.
		DATE OF NAME CHANGE:	20130123

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HORWITZ & ASSOCIATES, INC.
		DATE OF NAME CHANGE:	20020415
</SEC-HEADER>
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<TYPE>144
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Document 1 - file: primary_doc.html

Document 1 - RAW XML: primary_doc.xml

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