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Legal Proceedings
9 Months Ended
Sep. 30, 2025
Legal Proceedings [Abstract]  
Legal Proceedings
14. Legal Proceedings
 
From time to time, we are involved in legal proceedings arising in the ordinary course of our business. Periodically, we evaluate the status of each legal matter and assess our potential financial exposure. If we consider the potential loss from any legal proceeding to be probable and we can reasonably estimate the amount, we accrue a liability for the estimated loss. The outcome of any proceeding is not determinable in advance. Therefore, we are required to use significant judgment to determine the probability of a loss and whether the amount of the loss is reasonably estimable. Our assessment of a potential liability and the amount of accruals we recorded are based only on the information available to us at the time. As additional information becomes available, we reassess the potential liability related to the legal proceeding and may revise our estimates.
 
On September 10, 2025, Arrowhead Pharmaceuticals, Inc., or Arrowhead, filed a lawsuit in the District of Delaware seeking a declaratory judgment that our patent US9,593,333 is invalid or not infringed by use of Arrowhead’s ApoCIII inhibitor plozasiran. On September 11, 2025, we filed suit in the Central District of California asserting infringement of that same patent by Arrowhead’s announced intention to commercialize plozasiran in November 2025. On October 8, 2025, we filed a motion to dismiss, or in the alternative, transfer Arrowhead’s Delaware suit in favor of the case we brought in the Central District of California. At present, both lawsuits remain pending.