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Revenues - Revenues (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Revenue:
Revenue	$ 156,719	$ 133,814	$ 740,381	$ 478,562
TRYNGOLZA Sales, Net [Member]
Revenue:
Revenue	31,792	0	57,353	0
Product Sales, Net [Member]
Revenue:
Revenue	31,792	0	57,353	0
SPINRAZA Royalties [Member]
Revenue:
Revenue	55,896	57,208	158,243	152,406
WAINUA Royalties [Member]
Revenue:
Revenue	13,320	5,371	33,107	10,278
Other Royalties [Member]
Revenue:
Revenue	6,478	4,228	18,461	17,352
Royalty [Member]
Revenue:
Revenue	75,694	66,807	209,811	180,036
Other Commercial Revenue [Member]
Revenue:
Revenue	8,112	8,924	27,359	27,324
Commercial Revenue [Member]
Revenue:
Revenue	115,598	75,731	294,523	207,360
Collaborative Agreement Revenue [Member]
Revenue:
Revenue	31,436	44,883	413,387	235,753
WAINUA Joint Development Revenue [Member]
Revenue:
Revenue	9,685	13,200	32,471	35,449
Research and Development Revenue [Member]
Revenue:
Revenue	$ 41,121	$ 58,083	$ 445,858	$ 271,202

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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