<SEC-DOCUMENT>0001104659-16-117236-index.html : 20160503
<SEC-HEADER>0001104659-16-117236.hdr.sgml : 20160503
<ACCEPTANCE-DATETIME>20160503172418
ACCESSION NUMBER:		0001104659-16-117236
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20160503
DATE AS OF CHANGE:		20160503
EFFECTIVENESS DATE:		20160503

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EXACT SCIENCES CORP
		CENTRAL INDEX KEY:			0001124140
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				204782291
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-211099
		FILM NUMBER:		161616558

	BUSINESS ADDRESS:	
		STREET 1:		441 CHARMANY DRIVE
		CITY:			MADISON
		STATE:			WI
		ZIP:			53719
		BUSINESS PHONE:		608-284-5700

	MAIL ADDRESS:	
		STREET 1:		441 CHARMANY DRIVE
		CITY:			MADISON
		STATE:			WI
		ZIP:			53719

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXACT CORP
		DATE OF NAME CHANGE:	20000919
</SEC-HEADER>
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<TYPE>S-8
<SEQUENCE>1
<FILENAME>a16-10330_1s8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: a16-10330_1s8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.6
<SEQUENCE>2
<FILENAME>a16-10330_1ex4d6.htm
<DESCRIPTION>EX-4.6
<TEXT>
Document 2 - file: a16-10330_1ex4d6.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.7
<SEQUENCE>3
<FILENAME>a16-10330_1ex4d7.htm
<DESCRIPTION>EX-4.7
<TEXT>
Document 3 - file: a16-10330_1ex4d7.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5
<SEQUENCE>4
<FILENAME>a16-10330_1ex5.htm
<DESCRIPTION>EX-5
<TEXT>
Document 4 - file: a16-10330_1ex5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>5
<FILENAME>a16-10330_1ex23d1.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 5 - file: a16-10330_1ex23d1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g103301kki001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: g103301kki001.jpg

</DOCUMENT>
</SEC-DOCUMENT>