<SEC-DOCUMENT>0001124140-21-000011-index.html : 20210105
<SEC-HEADER>0001124140-21-000011.hdr.sgml : 20210105
<ACCEPTANCE-DATETIME>20210105160228
ACCESSION NUMBER:		0001124140-21-000011
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20210105
DATE AS OF CHANGE:		20210105
EFFECTIVENESS DATE:		20210105

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EXACT SCIENCES CORP
		CENTRAL INDEX KEY:			0001124140
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				204782291
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-251900
		FILM NUMBER:		21505359

	BUSINESS ADDRESS:	
		STREET 1:		5505 ENDEAVOR LANE
		CITY:			MADISON
		STATE:			WI
		ZIP:			53719
		BUSINESS PHONE:		608-284-5700

	MAIL ADDRESS:	
		STREET 1:		5505 ENDEAVOR LANE
		CITY:			MADISON
		STATE:			WI
		ZIP:			53719

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXACT CORP
		DATE OF NAME CHANGE:	20000919
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>exas-20210105xsx8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: exas-20210105xsx8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.6
<SEQUENCE>2
<FILENAME>exas-20210105xex46.htm
<DESCRIPTION>EX-4.6
<TEXT>
Document 2 - file: exas-20210105xex46.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>exas-20210105xex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 3 - file: exas-20210105xex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>exas-20210105xex232.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 4 - file: exas-20210105xex232.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>5
<FILENAME>exas-20210105xex233.htm
<DESCRIPTION>EX-23.3
<TEXT>
Document 5 - file: exas-20210105xex233.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>image1a.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: image1a.jpg

</DOCUMENT>
</SEC-DOCUMENT>