<SEC-DOCUMENT>0001104659-21-057561-index.html : 20210429
<SEC-HEADER>0001104659-21-057561.hdr.sgml : 20210429
<ACCEPTANCE-DATETIME>20210429160717
ACCESSION NUMBER:		0001104659-21-057561
CONFORMED SUBMISSION TYPE:	DEFA14A
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20210429
DATE AS OF CHANGE:		20210429

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EXACT SCIENCES CORP
		CENTRAL INDEX KEY:			0001124140
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				204782291
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEFA14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35092
		FILM NUMBER:		21870531

	BUSINESS ADDRESS:	
		STREET 1:		5505 ENDEAVOR LANE
		CITY:			MADISON
		STATE:			WI
		ZIP:			53719
		BUSINESS PHONE:		608-284-5700

	MAIL ADDRESS:	
		STREET 1:		5505 ENDEAVOR LANE
		CITY:			MADISON
		STATE:			WI
		ZIP:			53719

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EXACT CORP
		DATE OF NAME CHANGE:	20000919
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEFA14A
<SEQUENCE>1
<FILENAME>tm212465d4_defa14a.htm
<DESCRIPTION>DEFA14A
<TEXT>
Document 1 - file: tm212465d4_defa14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>tm212465d4_defa14aimg001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: tm212465d4_defa14aimg001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>tm212465d4_defa14aimg002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: tm212465d4_defa14aimg002.jpg

</DOCUMENT>
</SEC-DOCUMENT>