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INCOME TAXES - Additional Information (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Expense (benefit) for income taxes |  |  |
Total income tax expense (benefit) | $ 2,403 | $ (9,064) | $ (246,881)
Deferred tax assets: |  |  |
Operating loss carryforwards | 477,420 | 553,320 |
Tax credit carryforwards | 104,580 | 87,579 |
Compensation related differences | 85,007 | 67,976 |
Lease liabilities | 47,118 | 51,560 |
Capitalized research and development | 191,468 | 108,117 |
Other temporary differences | 10,275 | 19,353 |
Tax assets before valuation allowance | 915,868 | 887,905 |
Less - Valuation allowance | (465,832) | (419,356) |
Total deferred tax assets | 450,036 | 468,549 |
Deferred tax liabilities |  |  |
Amortization | (415,064) | (435,991) |
Property, plant and equipment | (9,465) | (4,653) |
Lease assets | (35,786) | (40,674) |
Other temporary differences | (7,010) | (6,944) |
Total deferred tax liabilities | (467,325) | (488,262) |
Net deferred tax liabilities | $ (17,289) | $ (19,713) |
Differences between the effective income tax rate and the statutory tax rate |  |  |
U.S. Federal statutory rate | 21.00% | 21.00% | 21.00%
State taxes | 3.90% | 3.90% | 3.60%
Federal and state tax rate changes | 1.10% | (0.20%) | (0.30%)
Foreign tax rate differential | 0.00% | (0.10%) | (0.60%)
Acquired IPR&D asset expense | 0.00% | 0.00% | (0.80%)
Research and development tax credits | 7.60% | 2.30% | 0.70%
Stock-based compensation expense | (4.40%) | (2.00%) | 1.10%
Non-deductible executive compensation | (3.50%) | (0.40%) | (0.20%)
Transaction costs | 0.00% | 0.00% | (0.10%)
Other adjustments | (0.70%) | 0.00% | 0.00%
Other adjustments | (2.50%) | 1.20% | 1.20%
Valuation allowance | (23.70%) | (24.40%) | 3.70%
Effective tax rate | (1.20%) | 1.30% | 29.30%
Reconciliation of the amounts of unrecognized tax benefits |  |  |
Beginning of the period | $ 28,270 | $ 21,780 | $ 16,629
Increase due to current year tax positions | 7,447 | 5,861 | 5,363
Increase due to prior year tax positions | 1,108 | 629 | 0
Decrease due to prior year tax positions | (426) | 0 | (212)
Settlements | 0 | 0 | 0
Ending of the period | 36,399 | 28,270 | 21,780
Federal |  |  |
Expense (benefit) for income taxes |  |  |
Current expense (benefit): | 0 | 0 | 0
Deferred tax expense (benefit): | 2,395 | (3,292) | (222,693)
State |  |  |
Expense (benefit) for income taxes |  |  |
Current expense (benefit): | 2,266 | 2,170 | 1,388
Deferred tax expense (benefit): | (1,829) | (8,926) | (30,528)
Foreign |  |  |
Expense (benefit) for income taxes |  |  |
Current expense (benefit): | 2,561 | 1,131 | 4,898
Deferred tax expense (benefit): | $ (2,990) | $ (147) | $ 54

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