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LICENSE AND COLLABORATION AGREEMENTS - Mayo (Details) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2024	Sep. 30, 2024	Jun. 30, 2024	Mar. 31, 2024	Dec. 31, 2023	Sep. 30, 2023	Jun. 30, 2023	Mar. 31, 2023	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Oct. 31, 2017
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Research and development	$ 97,709	$ 101,487	$ 121,145	$ 110,869	$ 115,184	$ 111,707	$ 104,356	$ 95,680	$ 431,210	$ 426,927	$ 394,191
Licensing Agreements | Mayo
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Time period after the last licensed patent expires that the license agreement will remain in effect									5 years
Licensing Agreements | Mayo | Sales Milestone Range Three
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Amount agreed to be paid upon reaching the specified amount of net sales												$ 3,000

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