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Sale of Nonfinancial Assets - Additional Information (Details) - USD ($) $ in Thousands |  | 3 Months Ended | 6 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Mar. 31, 2022 | Jun. 30, 2022 | Jun. 30, 2022 | May 31, 2022 | Mar. 04, 2022 | Dec. 31, 2021 | [1]
Asset Acquisition [Line Items] |  |  |  |  |  |
Proceeds from sale of priority review voucher |  |  | $ 110,000 |  |  |
Loss on sale of certain assets |  |  | 6,261 |  |  |
Intangible assets, net |  | $ 29,908 | 29,908 |  |  | $ 44,934
Priority Review Voucher |  |  |  |  |  |
Asset Acquisition [Line Items] |  |  |  |  |  |
Definitive agreement to sell |  |  |  | $ 110,000 |  |
Proceeds from sale of priority review voucher |  |  | 110,000 |  |  |
Gain recognized, net of transactions costs |  | 107,900 | 107,900 |  |  |
Origin-Sentynl APA |  |  |  |  |  |
Asset Acquisition [Line Items] |  |  |  |  |  |
Upfront payment received | $ 10,000 |  |  |  |  |
Intangible assets, net |  | $ 16,300 | 16,300 |  |  |
Origin-Sentynl APA | Other income (expense), net |  |  |  |  |  |
Asset Acquisition [Line Items] |  |  |  |  |  |
Loss on sale of certain assets |  |  | $ 6,300 |  |  |
Origin-Sentynl APA | Maximum [Member] |  |  |  |  |  |
Asset Acquisition [Line Items] |  |  |  |  |  |
Potential sales milestone payments |  |  |  |  | $ 4,500 |
[1] | The condensed consolidated balance sheet as of December 31, 2021 is derived from the audited consolidated financial statements as of that date.

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