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Net Loss Per Share - Schedule of Common Stock Equivalents were Excluded from Computation of Diluted Net Loss per Share (Detail) - shares | 3 Months Ended
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Mar. 31, 2023 | Mar. 31, 2022
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 55,126,084 | 65,762,715
Unvested RSAs |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 507,167 | 1,453,153
Unvested RSUs |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 10,878,865 | 6,855,291
Unvested Performance-Based RSUs |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 7,875 | 87,538
Common Stock Options Issued and Outstanding |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 12,262,353 | 11,831,697
Estimated Shares Issuable Under Performance-Based Milestone Compensation Arrangements |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 10,845,633 | 24,875,491
Estimated Shares Issuable Under the ESPP |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 42,898 | 78,252
Assumed Conversion of 2027 Notes |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 12,878,305 | 12,878,305
Assumed Conversion of 2029 Notes |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 7,702,988 | 7,702,988

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI https://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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