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Fair Value Measurements - Additional Information (Details) - USD ($) | 3 Months Ended |  |  |  |
--- | --- | --- | --- | --- | ---
Mar. 31, 2023 | Mar. 31, 2022 | Dec. 31, 2022 | Feb. 02, 2021 | Jan. 28, 2021 | Mar. 09, 2020
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Fair value assets, transfers between Level 1, Level 2 or Level 3 | $ 0 |  | $ 0 |  |  |  |
Fair value liabilities, transfers between Level 1, Level 2 or Level 3 | 0 |  | 0 |  |  |  |
Equity security investment | 49,803,000 |  | 43,653,000 | [1] |  |  |
Gains and losses from investment in equity securities | 964,000 | $ (12,866,000) |  |  |  |  |
Estimated fair value of outstanding term loan | 377,400,000 |  | 377,200,000 |  |  |  |
LianBio |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Equity security investment | 9,800,000 |  | 8,200,000 |  |  |  |
Level 1 |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Equity security investment | 40,000,000.0 |  | 35,500,000 |  |  |  |
2029 Notes |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Debt Instrument face amount | 747,500,000 |  |  |  | $ 747,500,000 | $ 717,500,000 |
Estimated fair value of notes payable | 480,400,000 |  | 314,000,000.0 |  |  |  |
2027 Notes |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Debt Instrument face amount | 550,000,000.0 |  |  |  |  |  | $ 550,000,000.0
Estimated fair value of notes payable | $ 416,600,000 |  | $ 218,600,000 |  |  |  |
[1] | The condensed consolidated balance sheet as of December 31, 2022 is derived from the audited consolidated financial statements as of that date.

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