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v3.23.1

Condensed Consolidated Statements of Redeemable Convertible Noncontrolling Interests and Stockholders' Deficit (Unaudited) - USD ($) $ in Thousands | Total | Equity Compensation Plans | Employee Stock Purchase Plan | Satisfy Tax Withholding | Redeemable Convertible Noncontrolling Interests | Common Stock | Common Stock Equity Compensation Plans | Common Stock Employee Stock Purchase Plan | Common Stock Satisfy Tax Withholding | Treasury Stock | Additional Paid-in Capital | Additional Paid-in Capital Equity Compensation Plans | Additional Paid-in Capital Employee Stock Purchase Plan | Additional Paid-in Capital Satisfy Tax Withholding | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit | Parent | Parent Equity Compensation Plans | Parent Employee Stock Purchase Plan | Parent Satisfy Tax Withholding | Non-controlling Interests
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2021 | [1] | $ (867,002) |  |  |  |  |  |  | $ 154 |  |  |  | $ (275,000) | $ 841,530 |  |  |  | $ (132) | $ (1,436,966) | $ (870,414) |  |  |  | $ 3,412
Temporary equity, beginning balance at Dec. 31, 2021 | [1] |  |  |  |  |  | $ 1,423 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Beginning balance, shares at Dec. 31, 2021 | [1] |  |  |  |  |  |  |  | 147,343,323 |  |  |  | 6,191,761 |  |  |  |  |  |  |  |  |  |  |
Issuance of shares |  |  |  | $ 104 | $ 966 |  |  |  |  |  |  |  |  |  | $ 104 | $ 966 |  |  |  |  | $ 104 | $ 966 |  |
Issuance of shares, shares |  |  |  |  |  |  |  |  |  | 229,926 | 127,635 |  |  |  |  |  |  |  |  |  |  |  |  |
Repurchase of shares to satisfy tax withholding |  |  |  |  |  | $ (110) |  |  |  |  |  |  |  |  |  |  | $ (110) |  |  |  |  |  | $ (110) |
Repurchase of shares to satisfy tax withholding, shares |  |  |  |  |  |  |  |  |  |  |  | (12,491) |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation |  | 25,423 |  |  |  |  |  |  |  |  |  |  |  | 25,423 |  |  |  |  |  | 25,423 |  |  |  |
Issuance of noncontrolling interests |  | 89 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 89
Transfers from (to) noncontrolling interests |  | 48 |  |  |  |  |  |  |  |  |  |  |  | (317) |  |  |  |  |  | (317) |  |  |  | 365
Temporary Equity, transfers from (to) noncontrolling interest |  |  |  |  |  |  | (47) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Unrealized gain (losses) on available-for-sale securities |  | (251) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (251) |  | (251) |  |  |  |
Net loss |  | (200,290) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (196,397) | (196,397) |  |  |  | (3,893)
Temporary Equity, net loss |  |  |  |  |  |  | (1,040) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance at Mar. 31, 2022 |  | (1,041,023) |  |  |  |  |  |  | $ 154 |  |  |  | $ (275,000) | 867,596 |  |  |  | (383) | (1,633,363) | (1,040,996) |  |  |  | (27)
Temporary equity, ending balance at Mar. 31, 2022 |  |  |  |  |  |  | 336 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance, shares at Mar. 31, 2022 |  |  |  |  |  |  |  |  | 147,688,393 |  |  |  | 6,191,761 |  |  |  |  |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2022 | [1] | (1,243,335) | [2] |  |  |  |  |  | $ 157 |  |  |  | $ (275,000) | 938,703 |  |  |  | (328) | (1,918,149) | (1,254,617) |  |  |  | 11,282
Temporary equity, beginning balance at Dec. 31, 2022 |  | (1,589) |  |  |  |  | (1,589) | [1] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Beginning balance, shares at Dec. 31, 2022 | [1] |  |  |  |  |  |  |  | 150,625,572 |  |  |  | 6,191,761 |  |  |  |  |  |  |  |  |  |  |
Issuance of shares |  |  |  | $ 193 | $ 1,809 |  |  |  |  | $ 1 |  |  |  |  | $ 192 | $ 1,809 |  |  |  |  | $ 193 | $ 1,809 |  |
Issuance of shares, shares |  |  |  |  |  |  |  |  |  | 834,427 | 192,200 |  |  |  |  |  |  |  |  |  |  |  |  |
Repurchase of shares to satisfy tax withholding |  |  |  |  |  | $ (512) |  |  |  |  |  |  |  |  |  |  | $ (512) |  |  |  |  |  | $ (512) |
Repurchase of shares to satisfy tax withholding, shares |  |  |  |  |  |  |  |  |  |  |  | (40,491) |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation |  | 24,330 |  |  |  |  |  |  |  |  |  |  |  | 24,330 |  |  |  |  |  | 24,330 |  |  |  |
Issuance of common stock under Follow-on offering |  | 143,016 |  |  |  |  |  |  | $ 9 |  |  |  |  | 143,007 |  |  |  |  |  | 143,016 |  |  |  |
Issuance of common stock under Follow-on offering, shares |  |  |  |  |  |  |  |  | 8,823,530 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of noncontrolling interests |  | 42 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 42
Transfers from (to) noncontrolling interests |  | (1,633) |  |  |  |  |  |  |  |  |  |  |  | (2,843) |  |  |  |  |  | (2,843) |  |  |  | 1,210
Temporary Equity, transfers from (to) noncontrolling interest |  |  |  |  |  |  | 1,633 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deconsolidation of PellePharm |  | 3,950 |  |  |  |  |  |  |  |  |  |  |  | 1,949 |  |  |  |  | 850 | 2,799 |  |  |  | 1,151
Temporary Equity, deconsolidation of PellePharm |  |  |  |  |  |  | 899 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Unrealized gain (losses) on available-for-sale securities |  | 316 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 316 |  | 316 |  |  |  |
Net loss |  | (141,585) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (140,156) | (140,156) |  |  |  | (1,429)
Temporary Equity, net loss |  |  |  |  |  |  | (1,147) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance at Mar. 31, 2023 |  | (1,213,409) |  |  |  |  |  |  | $ 167 |  |  |  | $ (275,000) | $ 1,106,635 |  |  |  | $ (12) | $ (2,057,455) | $ (1,225,665) |  |  |  | $ 12,256
Temporary equity, ending balance at Mar. 31, 2023 |  | $ (204) |  |  |  |  | $ (204) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Ending balance, shares at Mar. 31, 2023 |  |  |  |  |  |  |  |  | 160,435,238 |  |  |  | 6,191,761 |  |  |  |  |  |  |  |  |  |  |
[1] | The consolidated balances as of December 31, 2022 and 2021 are derived from the audited consolidated financial statements as of those dates.
[2] | The condensed consolidated balance sheet as of December 31, 2022 is derived from the audited consolidated financial statements as of that date.

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