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v3.25.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024 | Dec. 31, 2024
Operating activities: |  |  |  |  |
Net loss | $ (183,758) | $ (75,544) | $ (353,366) | $ (111,704) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |  |
Stock-based compensation |  |  | 63,123 | 38,511 |
Losses on extinguishments of debt | 0 | 0 | 21,155 | 26,590 |
Accretion of debt |  |  | 53,106 | 3,683 |
Depreciation and amortization |  |  | 2,601 | 3,170 |
Noncash lease expense |  |  | 2,230 | 2,093 |
Net loss from equity method investments | 20,189 | 7,925 | 35,745 | 7,925 |
Gain on deconsolidation of a subsidiary |  |  | 0 | (126,294) |
Gain from investment in equity securities, net |  |  | 0 | (8,136) |
Dividend from investment in equity securities |  |  | (2,302) | 0 |
Other noncash adjustments, net |  |  | (5,464) | (1,911) |
Changes in operating assets and liabilities: |  |  |  |  |
Accounts receivable, net |  |  | (72,146) | 1,091 |
Inventories |  |  | (16,582) | 0 |
Prepaid expenses and other current assets |  |  | (22,745) | (6,506) |
Other assets |  |  | (174) | 942 |
Accounts payable |  |  | 16,516 | 8,858 |
Accrued compensation and benefits |  |  | (15,637) | (8,378) |
Accrued research and development liabilities |  |  | (2,977) | 7,067 |
Operating lease liabilities |  |  | (3,117) | (2,981) |
Deferred revenue |  |  | (6,491) | 22,236 |
Other current liabilities |  |  | 26,609 | (1,090) |
Net cash used in operating activities |  |  | (279,916) | (144,834) |
Investing activities: |  |  |  |  |
Purchases of marketable securities |  |  | (7,908) | (93,811) |
Maturities of marketable securities |  |  | 0 | 55,000 |
Purchases of investments in equity securities |  |  | 0 | (20,271) |
Proceeds from sales of investments in equity securities |  |  | 0 | 63,229 |
Proceeds from special cash dividends received from investment in equity securities |  |  | 0 | 25,682 |
Payment for intangible assets |  |  | (6,095) | (3,190) |
Purchases of property and equipment |  |  | (594) | (749) |
Decrease in cash and cash equivalents resulting from deconsolidation of subsidiaries |  |  | 0 | (98) |
Net cash provided by (used in) investing activities |  |  | (14,597) | 25,792 |
Financing activities: |  |  |  |  |
Repurchases of common stock |  |  | (48,276) | 0 |
Proceeds from royalty obligation under Royalty Purchase Agreement (as described in Note 10) |  |  | 300,000 | 0 |
Issuance costs associated with royalty obligation under Royalty Purchase Agreement |  |  | (2,012) | 0 |
Repayment of term loans |  |  | (459,000) | (473,417) |
Repayment of deferred royalty obligation |  |  | (2,005) | 0 |
Proceeds from issuance of common stock through public offerings, net |  |  | 0 | 314,759 |
Proceeds from common stock issuances under ESPP |  |  | 3,237 | 2,364 |
Proceeds from stock option exercises, net of repurchases |  |  | 9,680 | 778 |
Transactions with noncontrolling interests |  |  | 1,550 | 0 |
Repurchase of RSU shares to satisfy tax withholding |  |  | (3,771) | (4,679) |
Net cash provided by financing activities |  |  | 362,369 | 273,819 |
Net increase in cash, cash equivalents and restricted cash |  |  | 67,856 | 154,777 |
Cash, cash equivalents and restricted cash at beginning of period |  |  | 683,244 | 394,732 | $ 394,732
Cash, cash equivalents and restricted cash at end of period | 751,100 | 549,509 | 751,100 | 549,509 | 683,244
Supplemental Disclosure of Cash Flow Information: |  |  |  |  |
Cash paid for interest |  |  | 23,271 | 49,046 |
Cash paid for income taxes |  |  | 1,153 | 0 |
Supplemental Disclosures of Noncash Investing and Financing Information: |  |  |  |  |
Recognized intangible asset recorded to "Other current liabilities" |  |  | 2,400 | 0 |
Unpaid public offering issuance costs |  |  | 0 | 18 |
Deferred and unpaid issuance costs recorded to "Other current liabilities" |  |  | 998 | 74 |
Unpaid property and equipment |  |  | 0 | 70 |
Transfers to noncontrolling interests |  |  | (1,640) | (1,929) |
Reconciliation of Cash, Cash Equivalents and Restricted Cash: |  |  |  |  |
Cash and cash equivalents | 748,953 | 407,958 | 748,953 | 407,958 | 681,101
Restricted cash - Included in "Prepaid expenses and other current assets" | $ 449 | $ 139,409 | $ 449 | $ 139,409 | $ 126
Restricted Cash, Current, Statement of Financial Position [Extensible Enumeration] | Prepaid Expense and Other Assets, Current | Prepaid Expense and Other Assets, Current | Prepaid Expense and Other Assets, Current | Prepaid Expense and Other Assets, Current | Prepaid Expense and Other Assets, Current
Restricted cash - Included in "Other assets" | $ 1,698 | $ 2,142 | $ 1,698 | $ 2,142 | $ 2,017
Restricted Cash, Noncurrent, Asset, Statement of Financial Position [Extensible List] | Other assets | Other assets | Other assets | Other assets | Other assets
Total cash, cash equivalents and restricted cash | $ 751,100 | $ 549,509 | $ 751,100 | $ 549,509 | $ 683,244
2031 Notes |  |  |  |  |
Financing activities: |  |  |  |  |
Proceeds from issuance of 2031 Notes |  |  | 575,000 | 0 |
Issuance costs and discounts associated with term loan under Amended Financing Agreement |  |  | (12,034) | 0 |
Financing Agreement |  |  |  |  |
Financing activities: |  |  |  |  |
Proceeds from term loan under Amended Financing Agreement (as described in Note 9) |  |  | 0 | 450,000 |
Issuance costs and discounts associated with term loan under Amended Financing Agreement |  |  | $ 0 | $ (15,986) |

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