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Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2025
Summary Of Significant Accounting Policies [Line Items]  
Summary of Cash, Cash Equivalents and Restricted Cash

Cash as reported in the accompanying condensed consolidated statements of cash flows includes the aggregate amounts of cash, cash equivalents and restricted cash as presented on the accompanying condensed consolidated balance sheets as follows:

 

 

 

June 30, 2025

 

 

December 31, 2024

 

 

 

(in thousands)

 

Cash and cash equivalents

 

$

748,953

 

 

$

681,101

 

Restricted cash — included in “Prepaid expenses and
other current assets”

 

 

449

 

 

 

126

 

Restricted cash, non-current — included in “Other assets

 

 

1,698

 

 

 

2,017

 

Total cash, cash equivalents and restricted cash

 

$

751,100

 

 

$

683,244

 

Summary of Other Current Liabilities

Other current liabilities presented on the condensed consolidated balance sheets consisted of the following balances:

 

 

 

June 30, 2025

 

 

December 31, 2024

 

 

 

(in thousands)

 

Accrued rebates and other related costs

 

$

19,065

 

 

$

210

 

Accrued interest

 

 

14,411

 

 

 

11,056

 

Accrued commercial liabilities

 

 

11,326

 

 

 

11,267

 

Accrued professional services

 

 

7,135

 

 

 

3,673

 

Deferred royalty obligations, current portion

 

 

4,812

 

 

 

144

 

Milestone liabilities

 

 

2,400

 

 

 

1,595

 

Income taxes payable

 

 

2,100

 

 

 

1,153

 

Other accrued liabilities

 

 

4,667

 

 

 

3,973

 

Total other current liabilities

 

$

65,916

 

 

$

33,071

 

Summary of Segment Information for Revenue, Significant Operating Expenses and Other Income (Expense), and Net Loss

The following table summarizes our segment information for significant operating expenses and includes a reconciliation to net loss:

 

 

 

Three Months Ended June 30,

 

 

Six Months Ended June 30,

 

 

 

2025

 

 

2024

 

 

2025

 

 

2024

 

 

 

(in thousands)

 

 

(in thousands)

 

Revenues:

 

 

 

 

 

 

 

 

 

 

 

 

License and services revenue

 

$

37,440

 

 

$

2,168

 

 

$

117,130

 

 

$

213,288

 

Net product revenue

 

 

71,501

 

 

 

 

 

 

108,240

 

 

 

 

Royalty revenue

 

 

1,624

 

 

 

 

 

 

1,828

 

 

 

 

Total revenues, net

 

 

110,565

 

 

 

2,168

 

 

 

227,198

 

 

 

213,288

 

Operating costs and expenses:

 

 

 

 

 

 

 

 

 

 

 

 

Cost of revenues:

 

 

 

 

 

 

 

 

 

 

 

 

Cost of license, services and royalty revenue

 

 

805

 

 

 

598

 

 

 

1,410

 

 

 

1,196

 

Cost of goods sold

 

 

2,848

 

 

 

 

 

 

4,882

 

 

 

 

Total cost of revenues

 

 

3,653

 

 

 

598

 

 

 

6,292

 

 

 

1,196

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research and development by significant program:

 

 

 

 

 

 

 

 

 

 

 

 

Acoramidis for the treatment and primary prevention
     of ATTR-CM

 

 

28,269

 

 

 

36,798

 

 

 

52,661

 

 

 

76,540

 

Infigratinib for achondroplasia and hypochondroplasia

 

 

30,191

 

 

 

22,098

 

 

 

58,125

 

 

 

43,283

 

BBP-418 for LGMD2I/R9

 

 

11,243

 

 

 

10,773

 

 

 

25,452

 

 

 

20,791

 

Encaleret for ADH1

 

 

13,128

 

 

 

10,608

 

 

 

28,587

 

 

 

23,152

 

Other development programs

 

 

10,536

 

 

 

9,693

 

 

 

21,966

 

 

 

41,977

 

Other research programs

 

 

17,864

 

 

 

24,725

 

 

 

35,871

 

 

 

49,924

 

Total segment research and development

 

 

111,231

 

 

 

114,695

 

 

 

222,662

 

 

 

255,667

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Selling, general and administrative

 

 

129,154

 

 

 

59,523

 

 

 

235,519

 

 

 

125,330

 

Restructuring, impairment and related charges

 

 

805

 

 

 

2,891

 

 

 

1,375

 

 

 

6,291

 

Total operating costs and expenses

 

 

244,843

 

 

 

177,707

 

 

 

465,848

 

 

 

388,484

 

Loss from operations

 

 

(134,278

)

 

 

(175,539

)

 

 

(238,650

)

 

 

(175,196

)

Other income (expense), net:

 

 

 

 

 

 

 

 

 

 

 

 

Interest income

 

 

3,898

 

 

 

5,195

 

 

 

9,283

 

 

 

9,270

 

Interest expense

 

 

(37,637

)

 

 

(22,937

)

 

 

(79,778

)

 

 

(46,408

)

Gain on deconsolidation of a subsidiary

 

 

 

 

 

126,294

 

 

 

 

 

 

126,294

 

Losses on extinguishments of debt

 

 

 

 

 

 

 

 

(21,155

)

 

 

(26,590

)

Net loss from equity method investments

 

 

(20,189

)

 

 

(7,925

)

 

 

(35,745

)

 

 

(7,925

)

Other income (expense), net

 

 

6,548

 

 

 

(632

)

 

 

14,779

 

 

 

8,851

 

Total other income (expense), net

 

 

(47,380

)

 

 

99,995

 

 

 

(112,616

)

 

 

63,492

 

Loss before income taxes

 

 

(181,658

)

 

 

(75,544

)

 

 

(351,266

)

 

 

(111,704

)

Income tax expense

 

 

2,100

 

 

 

 

 

 

2,100

 

 

 

 

Net loss

 

 

(183,758

)

 

 

(75,544

)

 

 

(353,366

)

 

 

(111,704

)

Net loss attributable to redeemable convertible
   noncontrolling interests and noncontrolling interests

 

 

1,855

 

 

 

2,088

 

 

 

4,041

 

 

 

3,032

 

Segment net loss attributable to common stockholders
   of BridgeBio

 

$

(181,903

)

 

$

(73,456

)

 

$

(349,325

)

 

$

(108,672

)

Schedule of Inventories Presented on Condensed Consolidated Balance Sheet

Inventories presented on the condensed consolidated balance sheet as of June 30, 2025 consisted of the following balances:

 

 

 

June 30, 2025

 

 

 

(in thousands)

 

Raw materials

 

$

11,463

 

Work in progress

 

 

1,065

 

Finished goods

 

 

5,749

 

Total inventories

 

$

18,277

 

Customer Concentration Risk  
Summary Of Significant Accounting Policies [Line Items]  
Schedule of Concentration, Percentage of Gross Revenues

The following table summarizes customers that represent 10% or greater of our consolidated total gross revenues:

 

 

Three Months Ended June 30,

 

Six Months Ended June 30,

 

2025

 

2024

 

2025

 

2024

Bayer (as described in Note 11)

*

 

16.7%

 

30.1%

 

61.4%

Kyowa Kirin Co., Ltd

*

 

66.2%

 

*

 

33.8%

Alexion (as described in Note 11)

22.3%

 

14.7%

 

12.0%

 

*

Customer A

19.4%

 

*

 

15.2%

 

*

Customer B

17.5%

 

*

 

13.7%

 

*

Customer C

13.3%

 

*

 

*

 

*

Customer D

12.2%

 

*

 

10.1%

 

*

* Represents less than 10% and/or not a customer in the applicable period.

Geographical Risk  
Summary Of Significant Accounting Policies [Line Items]  
Schedule of Concentration, Percentage of Gross Revenues

Total revenues, net is attributed to regions based on the location of our customers or partners.

 

 

Three Months Ended June 30,

 

Six Months Ended June 30,

 

2025

 

2024

 

2025

 

2024

U.S.

64.7%

 

17.2%

 

47.7%

 

4.8%

Europe, Middle East, and Africa (EMEA)

31.7%

 

16.7%

 

49.4%

 

61.4%

Asia-Pacific (APAC)

3.6%

 

66.1%

 

2.9%

 

33.8%

 

100.0%

 

100.0%

 

100.0%

 

100.0%