<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ex24ramachandra.txt
<DESCRIPTION>EXHIBIT 24 POWER OF ATTORNEY
<TEXT>
POWER OF ATTORNEY

     Know all by these presents, that the undersigned
hereby constitutes and appoints each of Safi R.
Bahcall, Ph.D., the President and Chief Executive
Officer of Synta Pharmaceuticals Corp.
(the "Company"), Keith S. Ehrlich, the Vice President,
Finance and Administration, Chief Financial Officer of
the Company, and Wendy E. Rieder, the Vice President,
Intellectual Property and Legal Affairs, General
Counsel of the Company, and Brian Keane, Ann Margaret
Eagleston, Garrett Winslow and Adisty Wilson of Mintz,
Levin, Cohn, Ferris, Glovsky and Popeo, P.C., signing
singly, with full power of substitution, the
undersigned's true and lawful attorney-in-fact to:

(1)  execute for and on behalf of the
undersigned, in the undersigned's capacity as an
officer, director and/or 10% shareholder of the
Company, forms and authentication documents for EDGAR
Filing Access;

(2)  do and perform any and all acts for and on
behalf of the undersigned which may be necessary or
desirable to complete and execute any such forms and
authentication documents;

(3)  execute for and on behalf of the
undersigned, in the undersigned's capacity as an
officer, director and/or 10% shareholder of the
Company, Forms 3, 4 and 5 in accordance with Section
16(a) of the Securities Exchange Act of 1934 and the
rules thereunder;

(4)  do and perform any and all acts for and on
behalf of the undersigned which may be necessary or
desirable to complete and execute any such Form 3, 4
or 5 and timely file such form with the United States
Securities and Exchange Commission and any stock
exchange or similar authority; and

(5)  take any other action of any type whatsoever
in connection with the foregoing which, in the opinion
of such attorney-in-fact, may be of benefit to, in the
best interests of, or legally required by the
undersigned, it being understood that the documents
executed by such attorney-in-fact on behalf of the
undersigned pursuant to this Power of Attorney shall
be in such form and shall contain such terms and
conditions as such attorney-in-fact may approve in
such attorney-in-fact's discretion.

     The undersigned hereby grants to each such
attorney-in-fact full power and authority to do and
perform any and every act and thing whatsoever
requisite, necessary, or proper to be done in the
exercise of any of the rights and powers herein
granted, as fully to all intents and purposes as the
undersigned might or could do if personally present,
with full power of substitution or revocation, hereby
ratifying and confirming all that such attorney-in-
fact, or such attorney-in-fact's substitute or
substitutes, shall lawfully do or cause to be done by
virtue of this power of attorney and the rights and
powers herein granted.  The undersigned acknowledges
that the foregoing attorneys-in-fact, in serving in
such capacity at the request of the undersigned, are
not assuming, nor is the Company assuming, any of the
undersigned's responsibilities to comply with Section
16 of the Securities Exchange Act of 1934, as amended.

     This Power of Attorney shall remain in full force
and effect until the undersigned is no longer required
to file Forms 3, 4 and 5 with respect to the
undersigned's holdings of and transactions in
securities issued by the Company, unless earlier
revoked by the undersigned in a signed writing
delivered to the foregoing attorneys-in-fact.

     IN WITNESS WHEREOF, the undersigned has caused
this Power of Attorney to be executed this 28th day of
February 2013.


/s/ Sumant Ramachandra
Signature

Name: Sumant Ramachandra

</TEXT>
</DOCUMENT>
