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Commitments and Contingencies (Details) - Research, Development and Commercialization Agreement - Hoffmann-La Roche ("Roche") - USD ($)	9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017
Commitments and Contingencies
Remainder of future milestone payments	$ 10,000,000
Licensed product sales	$ 0	$ 0

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