<SEC-DOCUMENT>0000950170-25-006816.txt : 20250117
<SEC-HEADER>0000950170-25-006816.hdr.sgml : 20250117
<ACCEPTANCE-DATETIME>20250117173003
ACCESSION NUMBER:		0000950170-25-006816
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250117
DATE AS OF CHANGE:		20250117

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MADRIGAL PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001157601
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-33277
		FILM NUMBER:		25539709

	BUSINESS ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE, SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428
		BUSINESS PHONE:		404-380-9263

	MAIL ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE, SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SYNTA PHARMACEUTICALS CORP
		DATE OF NAME CHANGE:	20010815

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Taub Rebecca
		CENTRAL INDEX KEY:			0001423898
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		144

	MAIL ADDRESS:	
		STREET 1:		750 BATTERY STREET, SUITE 330
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94111
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<headerData>
<submissionType>144</submissionType>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001423898</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>
</filerInfo>
</headerData>
<formData>
<issuerInfo>
<issuerCik>0001157601</issuerCik>
<issuerName>Madrigal Pharmaceuticals, Inc.</issuerName>
<secFileNumber>001-33277</secFileNumber>
<issuerAddress>
<street1 xmlns="http://www.sec.gov/edgar/common">Four Towers Bridge</street1>
<street2 xmlns="http://www.sec.gov/edgar/common">200 Barr Harbor Drive, Suite 200</street2>
<city xmlns="http://www.sec.gov/edgar/common">West Conshohocken</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">PA</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">19428</zipCode>
</issuerAddress>
<issuerContactPhone>267-824-2827</issuerContactPhone>
<nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Rebecca Taub</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
<relationshipsToIssuer>
<relationshipToIssuer>Officer</relationshipToIssuer>
<relationshipToIssuer>Director</relationshipToIssuer>
</relationshipsToIssuer>
</issuerInfo>
<securitiesInformation>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<brokerOrMarketmakerDetails>
<name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
<address>
<street1 xmlns="http://www.sec.gov/edgar/common">1 New York Plaza, 8th Floor</street1>
<city xmlns="http://www.sec.gov/edgar/common">New York</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">10004</zipCode>
</address>
</brokerOrMarketmakerDetails>
<noOfUnitsSold>1689</noOfUnitsSold>
<aggregateMarketValue>460742.31</aggregateMarketValue>
<noOfUnitsOutstanding>21810407</noOfUnitsOutstanding>
<approxSaleDate>01/17/2025</approxSaleDate>
<securitiesExchangeName>Nasdaq Stock Market</securitiesExchangeName>
</securitiesInformation>
<securitiesToBeSold>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<acquiredDate>01/16/2025</acquiredDate>
<natureOfAcquisitionTransaction>Restricted Stock Unit Grant</natureOfAcquisitionTransaction>
<nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
<isGiftTransaction>N</isGiftTransaction>
<amountOfSecuritiesAcquired>1689</amountOfSecuritiesAcquired>
<paymentDate>01/16/2025</paymentDate>
<natureOfPayment>Vesting of Restricted Stock Units</natureOfPayment>
</securitiesToBeSold>
<nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
<remarks>The sale of shares of common stock reported on this Form 144 represents the sale of shares pursuant to a sell-to-cover transaction in order to satisfy tax withholding obligations in connection with the vesting of Restricted Stock Units previously granted to the Reporting Person.</remarks>
<noticeSignature>
<noticeDate>01/17/2025</noticeDate>
<signature>/s/ Rebecca Taub</signature>
</noticeSignature>
</formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
