v3.19.3.a.u2

Balance Sheet Components - Property and Equipment, Net (Details) - USD ($) | 12 Months Ended |
--- | --- | ---
Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017 | Jan. 01, 2019
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | $ 296,079,000 |  |  |
Less: Accumulated depreciation | (94,584,000) |  |  |
Property and equipment, net | 201,495,000 |  |  |
Property, plant and equipment, gross |  | $ 276,433,000 |  |
Less: Accumulated depreciation |  | (64,456,000) |  |
Property and equipment, net |  | 211,977,000 |  | $ 209,494,000
Depreciation and amortization | 31,021,000 | 24,862,000 | $ 20,537,000 |
Building |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 0 |  |  |
Property, plant and equipment, gross |  | 140,442,000 |  |
Laboratory equipment |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 108,257,000 |  |  |
Property, plant and equipment, gross |  | 96,907,000 |  |
Leasehold improvements |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 152,426,000 |  |  |
Property, plant and equipment, gross |  | 13,741,000 |  |
Furniture, fixtures and other |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 3,316,000 |  |  |
Property, plant and equipment, gross |  | 2,122,000 |  |
Computer equipment and software |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 11,985,000 |  |  |
Property, plant and equipment, gross |  | 11,513,000 |  |
Internally developed software |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 7,020,000 |  |  |
Property, plant and equipment, gross |  | 7,020,000 |  |
Property and equipment, net |  | 0 |  |
Right-of-use asset, financing |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | 9,853,000 |  |  |
Construction in progress |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Property, plant and equipment, gross | $ 3,222,000 |  |  |
Property, plant and equipment, gross |  | $ 4,688,000 |  |

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