v3.19.3.a.u2

CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Revenue: |  |  |
Total revenue | $ 60,209 | $ 135,068 | $ 205,825
Operating expenses: |  |  |
Research and development | 496,309 | 454,082 | 410,459
General and administrative | 109,620 | 94,252 | 64,722
Total operating expenses | 605,929 | 548,334 | 475,181
Loss from operations | (545,720) | (413,266) | (269,356)
Interest income | 38,530 | 27,023 | 15,235
Other (expense) income, net | (7,526) | 1,835 | (1,875)
Loss before (benefit from) provision for income taxes | (514,716) | (384,408) | (255,996)
(Benefit from) provision for income taxes | (695) | 326 | (80)
Net loss | (514,021) | (384,734) | (255,916)
Reconciliation of net loss to net loss attributable to common stockholders: |  |  |
Premium paid on repurchase of preferred stock | 0 | (4,127) | 0
Cumulative preferred stock dividends | 0 | (12,996) | (13,925)
Net loss attributable to common stockholders | $ (514,021) | $ (401,857) | $ (269,841)
Net loss per share attributable to common stockholders, basic and diluted (usd per share) | $ (1.55) | $ (4.95) | $ (4.18)
Weighted average common shares used in net loss per share attributable to common stockholders, basic and diluted (in shares) | 330,802,136 | 81,114,183 | 64,497,544
Collaboration revenue |  |  |
Revenue: |  |  |
Total revenue | $ 42,803 | $ 76,519 | $ 146,953
Collaboration revenue from related party (Note 14) |  |  |
Revenue: |  |  |
Total revenue | 5,233 | 45,993 | 30,021
Grant revenue |  |  |
Revenue: |  |  |
Total revenue | $ 12,173 | $ 12,556 | $ 28,851

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