v3.19.3.a.u2

Income Taxes - Narrative (Details) - USD ($) $ in Thousands | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2019 | Jan. 01, 2019 | Dec. 31, 2018
Income Tax Disclosure [Abstract] |  |  |
Increase in valuation allowance | $ 162,500 |  |
Operating Loss Carryforwards [Line Items] |  |  |
Decrease in accounts receivable | (5,032) | $ (8,948) | $ (11,686)
Decrease in deferred tax asset | (507,268) |  | $ (323,501)
Federal |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Net operating losses | 981,800 |  |
Net operating losses that begin to expire in 2030 | 380,100 |  |
Net operating losses that will carry-forward indefinitely | 601,700 |  |
Federal | Research and development |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Tax credit carry-forwards | 45,600 |  |
State |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Net operating losses | 978,800 |  |
Net operating losses that begin to expire in 2030 | 978,800 |  |
State | Research and development |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Tax credit carry-forwards | 23,900 |  |
State | Federal Orphan Drug |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Tax credit carry-forwards | 1,500 |  |
State | Investment tax credit |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Tax credit carry-forwards | $ 5,900 |  |
Accounting Standards Update 2014-09 |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Cumulative-effect adjustment |  | 27,984 |
Decrease in deferred revenue |  | 30,700 |
Decrease in accounts receivable |  | 2,700 |
Decrease in deferred tax asset |  | 8,400 |
Accounting Standards Update 2014-09 | Accumulated Deficit |  |  |
Operating Loss Carryforwards [Line Items] |  |  |
Cumulative-effect adjustment |  | $ 27,984 |

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