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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Operating activities |  |  |
Net loss | $ (747,064) | $ (514,021) | $ (384,734)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Stock-based compensation | 93,021 | 81,122 | 72,565
Depreciation and amortization | 31,251 | 31,021 | 24,862
Leased assets expensed | 62,286 | 0 | 0
Amortization/accretion of investments | 10,185 | (3,742) | (1,866)
Loss on disposal of property and equipment | 238 | 316 | 891
Changes in assets and liabilities: |  |  |
Accounts receivable | (1,385,191) | 7,216 | 832
Inventory | (46,527) | 0 | 0
Prepaid expenses and other assets | (241,041) | 9,751 | (5,289)
Right-of-use assets, operating leases | (10,542) | (5,664) | 0
Accounts payable | 11,875 | (23,964) | 15,017
Accrued liabilities | 388,392 | (3,362) | 8,787
Deferred revenue | 3,842,307 | (44,119) | (65,260)
Deferred lease obligation | 0 | 0 | 2,420
Operating lease liabilities | 11,792 | 12,647 | 0
Other liabilities | 5,989 | (6,169) | 910
Net cash provided by (used in) operating activities | 2,026,971 | (458,968) | (330,865)
Investing activities |  |  |
Purchases of marketable securities | (2,956,295) | (1,145,226) | (1,227,709)
Proceeds from maturities of marketable securities | 1,137,129 | 993,181 | 783,373
Proceeds from sales of marketable securities | 214,686 | 168,654 | 177,008
Purchases of property and equipment | (67,448) | (31,554) | (105,766)
Net cash used in investing activities | (1,671,928) | (14,945) | (373,094)
Financing activities |  |  |
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs | 0 | 0 | 661,111
Proceeds from offerings of common stock, net of issuance costs | 1,852,725 | 0 | 563,026
Repurchases of redeemable convertible preferred stock | 0 | 0 | (8,182)
Proceeds from issuance of common stock under equity plans | 179,643 | 47,259 | 1,427
Proceeds from purchase of common stock under employee stock purchase plan | 7,040 | 2,891 | 0
Charges to financing lease liabilities | (6,215) | 971 | 0
Reimbursement of assets under financing lease obligation | 0 | 0 | 11,635
Payments on financing lease obligation | 0 | 0 | (2,175)
Net cash provided by financing activities | 2,033,193 | 51,121 | 1,226,842
Net increase (decrease) in cash, cash equivalents and restricted cash | 2,388,236 | (422,792) | 522,883
Cash, cash equivalents and restricted cash, beginning of year | 247,699 | 670,491 | 147,608
Cash, cash equivalents and restricted cash, end of year | 2,635,935 | 247,699 | 670,491
Supplemental cash flow information |  |  |
Cash paid for income taxes | 572 | 416 | 294
Cash paid for interest | 8,528 | 5,585 | 2,998
Non-cash investing and financing activities |  |  |
Issuance costs included in accounts payable and accrued liabilities | 0 | 0 | 2,638
Purchases of property and equipment included in accounts payable and accrued liabilities | 17,617 | 4,676 | 12,892
Leasehold improvements included in prepaid and other current assets | 0 | 0 | 10,089
Lease financing obligation | $ 0 | $ 0 | $ 10,089

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