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Income Taxes - Significant Components of Deferred Tax Assets and Tax Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carry-forwards | $ 587,211 | $ 268,173
Stock-based compensation | 33,089 | 43,978
Capitalized licenses, research and development and start-up costs | 13,985 | 19,891
Tax credit carry-forwards | 99,024 | 77,222
Accrued expenses | 26,962 | 7,377
Deferred revenue | 29,785 | 53,475
Operating lease liabilities | 22,313 | 26,571
Lease financing obligation | 23,718 | 10,570
Capitalized inventory | 38,058 | 0
Other | 0 | 11
Total gross deferred tax assets | 874,145 | 507,268
Less: valuation allowance | (823,468) | (470,753)
Total deferred tax assets, net of valuation allowance | 50,677 | 36,515
Deferred tax liabilities: |  |
Financing right-of-use assets | (11,539) | (2,612)
Operating right-of-use assets | (20,349) | (24,944)
Fixed assets | (18,276) | (8,959)
Other | (513) | 0
Total deferred tax liabilities | (50,677) | (36,515)
Net deferred tax assets | $ 0 | $ 0

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