XML 172 R78.htm IDEA: XBRL DOCUMENT v3.20.4
Collaboration Agreements - Chiesi Agreement Composition of the Total Transaction Price (Details) - USD ($)
$ in Thousands
 1 Months Ended 12 Months Ended
Dec. 31, 2020
Dec. 31, 2020
Dec. 31, 2019
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]      
Remaining performance obligations $ 87,225 $ 87,225  
Contract with Customer, Liability, Noncurrent $ 177,419 177,419 $ 138,995
Chiesi agreement      
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]      
Initial research period 4 years    
Total collaboration revenue   $ 200  
Research extension period elected   1 year  
Research extension period 4 years    
Remaining performance obligations $ 42,496 $ 42,496  
Amounts included in contract liabilities at the beginning of the period   25,000  
Contract with Customer, Liability, Noncurrent 25,000 25,000  
Chiesi agreement | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2021-01-01      
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]      
Remaining performance obligations 17,300 17,300  
Chiesi agreement | Upfront payment      
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]      
Total collaboration revenue   25,000  
Remaining performance obligations 25,000 $ 25,000  
Chiesi agreement | Certain Development Regulatory And Commercial Milestone Events      
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]      
Amounts included in contract liabilities at the beginning of the period $ 405,000