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Property and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 416,550	$ 296,079
Less: Accumulated depreciation	(119,661)	(94,584)
Property and equipment, net	296,889	201,495
Depreciation and amortization	31,251	31,021	$ 24,862
Laboratory equipment
Property, Plant and Equipment [Line Items]
Property and equipment, gross	120,714	108,257
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property and equipment, gross	179,901	152,426
Furniture, fixtures and other
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,662	3,316
Computer equipment and software
Property, Plant and Equipment [Line Items]
Property and equipment, gross	13,398	11,985
Internally developed software
Property, Plant and Equipment [Line Items]
Property and equipment, gross	7,020	7,020
Right-of-use asset, financing
Property, Plant and Equipment [Line Items]
Property and equipment, gross	56,348	9,853
Construction in progress
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 34,507	$ 3,222

X

- Definition

The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.

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